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Homo sapiens (human) MIR3936 host gene (MIR3936HG) URS000075A913_9606

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MIR3936HG: MIR3936HG is a long non-coding RNA (lncRNA) that has been implicated in various biological processes and diseases. Knockdown of MIR3936HG using specific siRNAs has been shown to mimic the effects of EBV-miR-BART6-3p, a microRNA that suppresses EBV-associated cancer cell migration and invasion by targeting MIR3936HG and reversing the epithelial-mesenchymal transition (EMT) process [PMC6700302]. Elevated expression of MIR3936HG, on the other hand, has been found to enhance tumor cell migration and invasion, promoting EMT [PMC6700302]. In a study investigating the correlation between expression levels of necroptosis-related lncRNAs and immune checkpoints, MIR3936HG was found to be related to the expression level of PD-1 [PMC8883231]. Furthermore, MIR3936HG has been identified as one of the downregulated lncRNAs in various infection models [PMC9845402]. In cancer research, MIR3936HG is among the lncRNAs directly linked to several types of cancer including ovarian cancer, esophageal cancer, gastric carcinoma, myeloma, non-small cell lung cancer, colon cancer, colorectal cancer, and hepatocellular carcinoma [PMC9327231]. In colorectal cancer specifically, downregulation of MIR3936HG has been observed [PMC6836529]. Overall, these findings highlight the potential role of MIR3936HG in various biological processes and diseases.

Genome locations

Gene Ontology annotations

Sequence

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GCGCGUGCGCGCGGGGCACCCGCCGCCGACCAGGCAAGCCAGGCAGCAGGCGACCCAAGACCGUCCGCGGAGGAGACAAGCAAGCUGUCAUGUUAUAAGCAGCCCUUUGAGGGGUCCAUGUGAUGUCAAGGAAUGAAGUCUCUAGCCAACAUUUAAUGAGGAACUGAGGCCCACCAACAACCUUGAGUGAGCUUGGAAGUAGCUCCUUCAGCAUCAGUUGGGUGUCGAGAUGACUACUGACAGCUUGACUGCAACUUCAUGAGAGUCUUCUGGACCAGAACCACUCAAGUCAGGGUUUCCCCAUGUUGGUCAGCCUGGUCUCAAACUCCUGACUUCAGGUGAUCCACCUGCCUCAGCCUCCCAAAGCGCUGGGAUUACAGUUUCAGUUAUCUACGGCCAACUGGGUAAACCAAAUAGAUGCUCUUUACAAAUAUUUUUUAACUUCUUAAAAUAUCUCAUUGAGGAUUCCGUUCCAAGAUGGCCAAAUAGGAACAGCUCUGGUCUGCAGCUCCCAGUGUGAUCGACGCAGAAGACGGAUGAUUUCUGCAUUUCCAACUGAGGUACCAGUUGAAUGAAGAGAAGCACACCUCCUCCCCAGAACAGUACUGCAGCUAUGAUAUAACGCCUGGGCAGGGUUCGCAAUAGCAGCCAGGCUGUAAUGUAAGCUGGAAUUUCAAUCAAGGCAGAGAGGAAACAGUUCAGAUGGAGUCUUGCUCUGCUGCCCAGGCUGGAGUACAGUAGUGCGAUCAAGGCUCACUGGAACCUCCACCUCCUGGGUUCAAGUGAUUCUCCUGCCUCAGCCUCCCAAGUAGCUGGGAUUACAGCUGCCCGGACACGAAGGAGCCGAGGAGCACGCCUACGAAGAACAGGGAGGUGGUGAGGGGCACCUUCCAGUUGUCCUCACACACCAGAUUCCACUGCCAAGGAAGACAGCAUGAAGCGUGAGCCCAACCCUGAGGCAGACCUCAACCCCAGCCCAGCUCUGAGGGAAUAUUAGCACGGCUGGCGGGCAGACUCUCCUCCCCUGGGCCAGGAUAUUGCCUUUGUACAAAGGGCAUAGGCCUUGCAGCCCUGGGUUUGACUGGCCUGUGCCGGGACUGGGGAGAGUAACCUGGGGCAGGUCACUGCCCUCCCUGAAACUCAGGAUCCUCUUUGGAAAGGGAGGGUGAUGCUCCUACUCCGCUCGCAUUACAUAGCAAGAAGCCAGCCAAGGCCAUGGCUGUGACUGGUGACCCCUCAGCUGUGAGGCAGUCCAAAGUAAAGGUGGCACUGCAUCUUCAGAAGCCAGCCUAGUGCGGAGGGGAGGUGUUUGAAAAGCCCAAAGGGCAGGGCAGAGGGCAUGGCCACUUGGUCCAGGCGUAAAAUUUCUUUUCCCUUGUUGAAAAGUGCAAGUGGUUCCAGGAGCUCUGUGACUUUAUUUUCUGAGCAGGCCCCUCUGAGAAAUCAUGUGGUCCCUGGUCCACUCACGCCUAGGCCAAGCUUGUGGCCUGAUUCGGGGCCCCAUCGUUCUGGGGCCUACUUACUCCUCUCCAGGGCUCCCUAGCUCCCCUCCUACAUCCCUACACCCUCCUUCCCAUCCAGUCUUUCCAGAAGUGUGGUCCCUCCCAUUCCCUAGGGUCUGUGGGAUGCUGCUGCCCUAACAAGUCCCUGCCAGUGCAUCUACAAAAUGAGUUUCAGCCAGAGUUUCAGUUUGACUUAAGUCAAUUAAGCAACAUCUCAAGGGAGGUGACAAAAAUUUCAAAGUGUGUUUAGUGACCUUUCAUUUAUUAAAAACAAAUAAAUAAACAAACAGAUGCCAAUGA

Taxonomic tree

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Publications