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Homo sapiens (human) CFLAR antisense RNA 1 (CFLAR-AS1) URS000075A8C6_9606

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CFLAR-AS1: CFLAR-AS1 is a long non-coding RNA (lncRNA) that has been studied in relation to various diseases, including esophageal squamous cell carcinoma (ESCC) [PMC8268190]. In a study, the combination of Linc00152, CFLAR-AS1, and POU3F3 with CEA achieved a high area under the curve (AUC) of 0.955 [PMC8268190]. CFLAR-AS1 is involved in immune-related pathways such as the TNF signaling pathway and the NF-κB signaling pathway [PMC8750853]. Hu and colleagues reported that CFLAR-AS1 is significantly upregulated in ESCC patients compared to healthy controls [PMC7589026]. CFLAR-AS1 is involved in epigenetic regulation, as well as transcriptional and posttranscriptional regulation [PMC6613612]. It has been experimentally validated as a cancer-related gene according to the lncRNADisease 2.0 database [PMC7880362]. In another study by Hu et al., CFLAR-AS1 was found to be significantly upregulated in ESCC patients compared to healthy controls, with an AUC of 0.651 [PMC6142629].

Genome locations

Gene Ontology annotations

Sequence

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CAUGCAUACAGCCCAGUCUAACGUACAGGAUCAAAAAGAGACCUUAUUUCGGCUGGCAAUUACCUUACCCGCUUGUUCAUUAUCUGACUCCUGCACUCCUCCCAAGUGUUCAAUGUUAACCAGAUGGCAAAGUUAACCAGACAGAGGAAAUCCACAUAAUUACUCUAGAUGAAGCCCCCUAACUGCGGAUUAGAAGGAAAAGAGAUGAAGGGUGCUGCACUAAUAAUAACAACCAUUUUCAACCAAGGCAGGAUUCUGGGCCUAGAAUCUUCAGUGACAAAUUACCAGGAGAGGAGGAGGGAAAUGAAGAGCUGGAGGCCUAGGGAGAUGGUGUGAGGAGAGGAGACUGUGCCUUUCCACUUCUUAAUAAUUAAUGUUCUCCUGCUGCUCUGAGUCUGCAUCACCAGUGAUUCAGUUUGAGUCAGACAUCCAACAACAACUGAGCAAAAGAAUCAUCUCAGAUCCAAGCAAUGGUGACGCGCAGAUAGAAGAGACUGAGGCCAACGACCAAAGCAAAGGACAGCAGAACUGACUGACACAGCUCAGAAAAUAUCCAAAGCUCUGUAUGCUCUGGAAAGGAAGACAAGAAAUGCUAAAGACUCUGGAUAUUGCUCUGUUUCUAUAAGGUCCCACCCAUAUACCAUCUCUUCUUUUGGAUUUCCUUUGGCAGGGUUCCCUUGUAUGGAAGUUCUCAGGAGAACAACACUCUCAGAGUCCCACUGUCUCAAAGAAUUCUUAAUGGACAGCUAUACUUGGCCCCAAGGUUUCAACCUCACACUGAAGAAAGUGACAUAAGAAAACACAAGUCCCAGUGCUAUCAGGGGCUAUCUGGAAAAGCUGCUUAAACAGCAAGUGAAAGAAGGCUCUCCCCUACCCCGUUCUAGACUCACCCUGAAGUUAUUUGAAGGAUCCUUGAGACUCUUUUGGAUUGCUGCUUGGAGAACAUUCCUGUAACUUGUCCCUGCUCCUUGAACUAUAAAAGCAGAAGGGAGGUACUGAGUUAAAACUUACAAAUUAUUAUCAAAUAAAUCUUCAAUAGUG

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Publications