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bta-miR-2904: Bta-mir-2904 is a miRNA that has been identified as one of the top differentially expressed miRNAs [PMC9810022]. It has been associated with a bacterial cluster comprising Prevotella, Bacteroides, Ruminococcus, Propionibacterium, and Klebsiella [PMC6708143]. Bta-mir-2904 exhibits the highest diversity of isomiRs, with numerous variants at both the 5' and 3' ends [PMC4609085]. It has also been found to be highly expressed in certain groups compared to control groups, such as in the SA group [PMC6896338] and LF bulls [PMC8329915]. Bta-mir-2904 has been shown to target genes such as IL1A and DEXH Asp-Glu-X-His box polypeptide 58 (DHX58) [PMC7943879]. In different studies, bta-mir-2904 has shown both upregulation and downregulation in expression levels compared to control groups or other conditions [PMC7943879] [PMC8903571] [PMC5414302] [PMC7519046]. Additionally, bta-mir-2904 is one of the miRNAs significantly enriched in HS-EVs compared to control-EVs [PMC7519046]. Overall, bta-mir-2904 exhibits differential expression patterns and potential target genes that may be associated with various biological processes.
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