hsa-mir-6891: Hsa-mir-6891 is an annotated microRNA (miRNA) encoded by intron 4 of the HLA-B gene [PMC5437213]. The pre-miRNA hairpin sequence of hsa-mir-6891 is evolutionarily conserved, with 90% sequence identity among six primate species [PMC5437213]. In contrast, the closest homolog of hsa-mir-6891 in the mouse genome has only 48% sequence conservation and does not encode an annotated miRNA [PMC5437213]. Hsa-mir-6891 is classified as one of the overmutated miRNA genes in various cancer types [PMC7648123]. The analysis identified hsa-mir-6891 as one of the candidate driver genes in Pan-Cancer, along with seven other miRNA genes [PMC7648123]. In addition to Pan-Cancer, hsa-mir-6891 was also identified as a candidate driver gene in CESC (Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma) [PMC7648123]. The weighted analysis and OncodriveFML analysis both identified hsa-mir-6891 as an overlapping miRNA gene in CESC and Pan-Cancer [PMC7648123].