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hsa-mir-6071: hsa-mir-6071 is a microRNA that was found to be significantly downregulated in a study on primary open-angle glaucoma (PEXG) [PMC8049460]. The study also identified several other downregulated miRNAs in PEXG, including hsa-miR-95-5p, hsa-miR-515-3p, hsa-mir-802, hsa-miR-1205, hsa-miR-3660, hsa-mir-3683, hsa -mir-3936, hsa-miR-4774 -5p, hsa-miR -6509 -3p, and hsa -miR -7843 -3p [PMC10000531]. On the other hand, ten miRNAs were found to be upregulated in PEXG including hsa-miR-202 -3p and hasmi-R3622a -3p [PMC10000531]. The expression levels of these miRNAs were found to have a significant impact on the expression of genes related to protein metabolism and various cellular processes [PMC10000531]. Furthermore, a network analysis predicted the involvement of several circRNAs (hsa_circ_0000324 and has_circ_0068797), miRNAs (hsa-miR3152 3p), hasmir6071), hasmi-R609), and hasmi-R675 5 p) as well as mRNAs (MAPK14 SYK CD86 TLR6) in PEXG [PMC9433285]. Additionally, several miRNAs including hasmir6071 have been associated with various cancers such as breast cancer (BC), colorectal cancer (CRC), and gastric cancer (GC) [PMC9522702]. Finally, a ceRNA network analysis identified hsa-mir-6071 as one of the miRNAs involved in the regulation of multiple mRNAs in a specific circRNA network [PMC9092689].
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