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Homo sapiens (human) MIR663A host gene (MIR663AHG) URS0000759F7F_9606

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MIR663AHG: MIR663AHG is a long non-coding RNA (lncRNA) that has been found to be higher in tumors compared to normal tissues in pancreatic cancer patients [PMC8197236]. It is a host gene of miR-663, which has been shown to be significantly downregulated in pancreatic cancer [PMC8197236]. MIR663AHG has also been identified as one of the top 10 candidate genes with significant differential expression in the circulating exosome RNAs of pancreatic cancer patients [PMC8197236]. In addition, MIR663AHG has been identified as one of the potential prognostic biomarkers for gastric cancer (GC) [PMC9667298]. It was found to be highly expressed in GC tissues and associated with a poor prognosis [PMC9667298]. Furthermore, MIR663AHG was shown to have weak positive correlations with GAGE1 and APOA1, and its expression was not significant with overall survival (OS) but showed a consistent tendency with survival analysis and Cox regression analysis [PMC9667298]. MIR663AHG has also been linked to Turner syndrome and its downregulation during phenotypic switch may lead to the de-repression of certain miRNAs and downregulation of TP53, ELN, and BCL2L11 [PMC8952224]. Overall, MIR663AHG is an lncRNA that shows differential expression in various cancers and may have prognostic implications.

Genome locations

Gene Ontology annotations

Sequence

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GGGCUUGGGCUGGUGACGCGUGCGCCGGCCGGCCGCCGAGGGGCUACCGUUCUGCCUCCGACCGGUCGUGUGUGGGUUUACUCGGAGGUGCUUUGCCUCUGAAGAAAAGAGAAAUACUAGGCUUUAGAAUUUCACCAUAUGAAUUUUGGGAGAGAGGAGCACAGUUCAGCCCAUAACUAACACACGACGGAAUGAAGUUGAUAAUAGUGAGACCUUGUUGGUACAAGACUAUGUAACAUAACCUGCGCUUCUCAACAAAGAAUUGCUUUUCUGACUUCUGCACUCAAUAGCAAGACAAAUCUCUCCUCUGCCUUCUCCUUAUCAGACUACUCAACAUGAAGGCAAUAAGAAUGAAGACCUCUAUGUAUAAUAAUUGACUUCCACUUAAUAAAUAAGGUUACUUGGUACACUGGUCGACAAAACCUUGAAAUGUUGAUGUUUAAGGGCUGUUGAUUGCUGGCAGCAAAGAAGUCCAACUGUGCUGGUACCCGAGAUAGCGUCUCCACAUUUUCUUCCAGGAUCAUCACCUUUGUUCUAAAUAGCUCCCACAUAGUGUGAACAGAAGUCAUAUGUUUUAGAUUUUCUGCCUUGGCACCCAGGAAACCAGUAUGAUUGAGUAAACAUAUUAAACUUCCUCUGCAUUUCCAGCCUGAACAGAUGUUGAGUACAAGCUGAUCCACCUACGUUCAACCUGAGAGAGUCCACAUCCACAGACUGUUUCAUUUCCCUUUUUCAAUUUACAUAGAAGCAUAGAUUCUUGCUGGCAUAUACAAAUGCGCCAUUUAAGGCAAUCAAAAAUGGUUCCACAUCUCAUCUGAUUUCCACAAUUGUUGCUGUAACGAUGGACUACUGAGGAGAGAGACAAUUUCUCUGGCACAUCUUCCCACAUUUUAGCAACAUGUUCAUGGAGAGCCAAUAUUCAGUAAUUACAGCCCAAUUCCUCACAAUUUCACAAUUCGCUAACAAUAUGCAUUUUCACAAUGUAAAGCUGAUUUUCCUUUAACCAAAUCAAACAUGAAAAGAUAGCUGCAUGCAAUGGGCAAUCUAGAUCAUUAGAAGAUUGAUGUAAAAUUAGAGGACACUGAGACUGGAAUAGAUUGCAAACUUCAGGGAGCUCAGAAAACUUGUAAACUCUACAUUUUGAGGAAAUAUGUUGUCGAUGCUUUUGCAACUCUAUGCAGUAACUUAACAAAUAAAGCCUUAAAGUAACUUAAAAAAAAAAAA

Taxonomic tree

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Publications