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Homo sapiens (human) long intergenic non-protein coding RNA 685 (LINC00685) URS0000759D41_9606

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LINC00685: LINC00685 is a non-coding gene located in the duplication in Xp22.33/Yp11.32, along with four coding genes, including SHOX [PMC8999496]. LINC00685 is expressed in various cell types with an unknown function [PMC9547805]. It has been found to be downregulated in the deep cortical layers of multiple sclerosis patients [PMC9547805]. In the testis, high expression of PPP2R3B is associated with low expression of LINC00685 [PMC4051606]. LINC00685 has been identified as a negative regulator of PPP2R3B, potentially affecting spermatogenesis [PMC4051606]. The expression levels of LINC00685 and PPP2R3B show an inverse relationship throughout spermatogenesis [PMC4051606]. The duplication DUP1A includes the duplication of LINC00685 and other genes [PMC4051606]. Distal variants downstream of LINC00685 have been reported in the database of genomic variants (DGV) [PMC4051606]. The Rep2 sequence has been found within the intronic region of LINC00685 on both X and Y chromosomes [PMC7572123]. In degenerative NPCs, LINC00685 is upregulated compared to normal NPCs [PMC9196128]. Overall, LINC00685 is a non-coding gene that may play a role in various cellular processes and has been implicated in spermatogenesis.

Genome locations

Gene Ontology annotations

Sequence

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GGGACCGGGCCGCUUCUUGUUCGGCGUGGGCGGCUCCUGGCAGACCCAUCCCGCGGUGCAGCCGCCGGCCCGGUAGGCGCCAGGACCCCGAGCCUCGGCGGCGGCGGCGGCGGCGGCAGCGCUGCCUUCACUCACCUCGUCCUCGCUCCCGUCCUACCCCGUUCCGCGCUGGGUGGAGUCCAAGUCUGAUUGCGAGAGUCCGGAACGCCGCCUCGGGGGCUUGACUCCAGCCCCGGGGAUCGAGAACGGCGCCCAGGGGUCCCUACGUCUGCCUUGGGGGCUCGAGUCCCGCCCUGGGCGUCCGUGACGUCGCCCAGGGGUCUCCACGUCUGUCCUGGAACCUGGAGAGCCGCCGUGGGGGCCCCGGAAGCCGCCCAGGAGUCCCCACGUCUGCCCUGGGGGCUCGAUCCAGCUCUGAGGGUCCUGAAGUCAGCUUUGGGGGUUCGAACCCAUCCAUCCCAGGGGUCCCUGAGUCUACAUUAGGGGCUGGAGUCCAGCCUUGAGGGUCUCCACUGCUGCCUUGGGGGCCUGGAUGGGAUCCAGCGGGUCUGAGUCCAGCCUCGGGAGCCCCUGCGGUGGAGCUCUGAGUGGGGCAGGGGCCUGGGAGAUGCCAGGAGGAUGAGAGCGGCGCCCCCCUGGUCCAGGGGACAGUAAGAGGCAGCCGGUCUCAGAGAAGCUACCCCAAAACUGUUACCCGUGGUGUGCAGAGCGUCCUGCAACCCCAGCCCUCACCAGGAUUUCUUGCGUUUUUCAGGAAAUCGGUUGUGAUUGGCAUGUUCCUUAAGCGUCUGCAGGAAGCCGAGGCCUUUUUGGUAUUUCAGGAGGGGUUGCUAACCCCCCUCCUUGUAGGAUCGGGGUAUCCCAGCUGCUAAUUCCCCUCCUAACAGCCCUGCAGCGCCUGGAUUGGAGGUGUGACAGGUGGCAUUUUUGGCCCGAAGUCCCUAGGCAGGACGGGUGGCUGUAGCCUGCGCGUUUGUGUAAAUUAACCUCCCUUUUUAGUUCUGUGAAGGGAGAACGUGAUUAGUUUAAAAUCACCUGCGUGAAAGAGGCUCUUGAUUAGUUUAAAAUCACCCACGUGAAAGGGGCUCUUGAUUAGCUUAAAAUCACCUGGGUGUUUCGUUUUAUCUCAGUUGGCCUCUGAAUGUUUAUCCUACAGCUUCCUGCAAGCUCCAGUCUACCUUCUAAGGGAAUAACGGGGCUCGUCUUUCUACGUUACUUUAUGUGGGAGUAGUUGUAAAACAGAAUGAGGGAGACCGCGGGGAUUGUGCGGAAAUGUAGCCACCGUUUACAUGUCGGGAGGCUGAGGUGGGAGGAUCGCUUGAGCCCAGGAGUUUGACACCAGCCUGGGCAACAUGGUAAGACCCCUUCUCUACCCUCCCCCCCAAAAAAAAAAUUUUAGUGUGGCAUGGUGGUGGGUGCCUGUGGUCCCAGCUACUCGGGACGCUGAGGUGGGAGGAUUGCUUGAGCCCAGGAGUUUGACACCAGCAUGGGCAAUAUGGUAAGACCCCAUUAUCUACAAAAAAAAAAAAAAA

Taxonomic tree

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Publications