v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) MSC antisense RNA 1 (MSC-AS1) URS00007599B7_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

MSC-AS1: MSC-AS1 is a long non-coding RNA (lncRNA) that has been studied in various contexts. In chondrocytes, depletion of MSC-AS1 was found to promote apoptosis, while overexpression of MSC-AS1 had the opposite effect [PMC8805978]. In ovarian cancer cell lines, MSC-AS1 was found to be expressed at lower levels compared to normal cells [PMC8403346]. In TMZ-resistant glioma cells, MSC-AS1 was shown to regulate CPEB4 expression by binding to miR-373-3p [PMC7873112]. In stomach cancer tissues, the expression level of MSC-AS1 was investigated and its potential therapeutic and prognostic value was explored [PMC8674534]. Silencing of MSC-AS1 in MGC-803 cells resulted in increased cell viability when PFKFB3 was restored [PMC7757144]. High expression of MSC-AS1 was found to promote the malignant behavior of nasopharyngeal cancer via the miR-524-5p/NR4A2 axis [PMC8791745]. In osteoporosis, MSC-AS1 was shown to inhibit disease development by promoting osteogenic differentiation through regulation of the miR1405p/BMP2 axis [PMC8588622]. Additionally, in diabetic nephropathy (DN), MSC AS1 acts as a sponge for miR325 [PMC8808114]. High expression levels of lncRNA MSC AS1 were associated with poorer 10-year progression-free interval in patients with stomach cancer [PMC8674534]. Finally, a study identified several lncRNAs including MSC AS 1 as prognostic indicators for hepatocellular carcinoma (HCC) that are associated with TGF-beta signaling and cellular apoptosis.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
AGGAUUUUUCCCAAGCCGGGAGAGCUGGCAGAUCAGAGAGGGACUUUCCAGAUAAAUCCCAUCUGGGGAAACGUUACUAUCUUCCACAAGCAAUUUUUCUAAAAAUGCAAAUGCUCUUUUAUAGAGCUCGGCCUUCCCUCCUUUAAGAAAGGGCUUGCCGAUUCAAACCUGCCCGACUCAGCUGGAUUAAGUUGGGCAAGGGAGAUUUGCCGUCAGUCUGCAACCUGGUGGCAGAUGGAGAUGGAACCAAGAUUUACCCUGGAAGUAGGAUAUUAGUCAAUGGCUGUCACUGGGGUACAAUGUUCAGAACGAUGCAAACAGACACGGAGGGUUGAUUCUUCUUCAGGGAAAUGGCUGGCCACUCCCUUGAUUUGGGAGAAACUAAACUGGCCUUCUCGUUCCCAGUCCCAGAACCUCCACCCCUUUCGAAUUCUUCCCAACGGGCUGACCCUGCCCGGCGCCCAGGAGCGCCCUGGGUAUCUCCUGGCUGCUCUCCCGAAUCCUUGCGCGCCGCGCCCCUACCAGGUUCACUGGGUGCACGUAGCCGUUCUCAUAGCGGUCCUCCUGCAACAGCUGCCGCAGUCUCGCUGUCUCCGCCUUCCGCUCCCUGGCGGAGGCGGAGGCCAGAGAGCGCUCCAAGGAAGACUAAAAACCCAGGCCGGGAAGCGCGGGGUGAGAAAGCGAGGUGGGUGGCGAGAGCGUGAGCGCCCCUCUGCUGACCCCGGGGAGCGUGGACUACGAGUUGGCGCCCAAGUCCAGAAUCCGCGCGCACCGCGGAAAAUAUUUGCAAUACCUGCCACGUCCAAGGUUCAGCUGAGGCCAAUGUAAAGCCAGUAUUAUAGGACACUUCUCAGACUGAGAGCCCAAUGUCGUUGGAAACCACUGGGCCACAGGAAAGGCAGGCUCUCUCAGUCCUGCUCCUGCCAUGGAAGAAGCCUGCUCCCACCAUGCCUUCUGCCACGAGUAAAAGUUCCCUGAGGCCUCCCCAGAAGCAGAUGCUGUCGUGCUUCCUGUAUAGCUGCAGAACUACUUCAAAUCAUCCCAACACCAGAGAACACUAAAUGACAGUGGACAGGAAGACAGUGUACCUUUUGCUCCUGAUGAUCGUAAGAACAACCUCCUUCCUCUUAUUGUGAAGUGCAAGGUGCAAAAAGGAGGCCUGCUGCUUGUUCAGGACUAUGUCAGCAUUGUGGCUCAGAAGAAGCGCAACGGCUUUGGCGUGGCCUUCCCUUGCAGCAAAGUGAAGUGCAGUGUUCUUUUGAAGAAAAACAGACACAGAAAACGUGGUGACAGUGUCUAAUCUGUCUUAUUUCACUGCUUAACUGCUUAAAAGACAUUAGCGACACUAUUUAAUACCAAAAUACAUAGCACUUAAAACUGGUGUUCAGAAUCAAGCUUCAAAAUAAUGAGUUUAUAGUUCUAGCAUGGUGUGUGUGCAUGUGUGGGAAGUGGAUCUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGAGAGAUAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAUGAAUUCCAAGGCAUUUGUUUUGUGUUGCUUUUGCAAUGGGAUGAUUCCACAAGGACAAAGGACAAGCUUUCAGGGUAAAGAUGUUGGGUUGAACACAGAAGAAAAUCCUCCUGAGAUUGAUCAUUUGUAGAACAGUGGCUUACAGAUUUGGGGCUUCACAAGCUUGUAAAUGUUUUUUAAAAUCAGAGACUGUUAUAAGUUUGCCCAUUUUUAGUUUCUCCACUUAAAGACUUUUUUUUUUUGAAAAAGGCAACAACAGUCUUCUAUCCCCAUCAUUUUAUGAACAAACGUACAUUUCAAAAGUUACUCUCCCCAAAGGAAGGAAAGACAUAAUAGCACAAUAAAGGGCAGCAUUUCAAAUCAAUACACUUCAAAAUAACACUUAUCUUAAUGAAAACUCACCCCUGCCUUCAUUUCUCUGGACCUACCAGGGAGUAAACGCUUUACCAUCAAAUUUCAUUGGCCUGUGGACCUCGCUGCUCUGUGAGACUGGAGGUUUCCCCAACAUUCACCCACCCCUUGGUAUUCUCCCAAUUCUGUUGCCUUUUGAUUCAUACUUCACCUCAAGAAUCCACUUGCUAAACACCCAACAAAAGGCUGGGAAUAGAGCAAGGAAGGUAAAAGGUGUCUAGGAGAGUUUUCUGGCAAUGUUGGAAGUUUCUGCUAUAUUGAGAUUUUGGGUAAGCAUGAGGACCGCAGUACAUACCCCGUCUUCAUCCAGGCGAUCUGUGCACUUCAAAUUAGUAUCAAGAAUGACCUUCAUGGUCUGAGUGUACCCGCCCAUGGACGCAUGAUGCAAAGCUGUCCAGCCAUUGUGGUCACUGGUAAAGAGUUAAGAAAAGAUGUGUGCAUACACUUAACAGAUGAAAUGCGGGAUGGGAUGCCACUUGGCUUAUUCUAGGUAAAUCUGAUGACAACAAAAAGCAUUAUUGAGAUCUGGCAACUAAAUAUUUAUAAAACAUUUAUAAUAAAUGAGCUAAUUCCAAGCUCAAUGAUCUUAAAUGACCUAUUUCUAAUGUGAUUCAUACACGUUUUUUACUUAGUGGUUUAAAAUAUGAAAGUAUAUAAACACAUUACCAAACACUUUGGGGUAGGAGAAGUACGCUUAGCAUGUCUGUGUCAUACCUAAUUUUUUUAAAGCUAUAAUGAACUGAUACACAUCAAUUUAAAUCUUGUUUUAUUCUUUCAAUGAACACUGUAUCAAAAUUUUUUUAUGAAGUAAUGUUAGUCUUUGUGGUCAAUAGUUAUUGGUAAUACUACUAGUAAUAUGAUACAUGGCUAUAAGAUGCUUAGCUUAGUGUCAGUUAUUAUUCUAAGAGUUUAAAUCUAAAAAGCUUCCCUCUUGUGCUCUGAAAAAUGCUUACUCAAUUGCUUUGAAAAAUGUUUAUCCUUUUCCACAGAAAUUCAAGAUGUAAAUACAACAAAGCCUUGUCAUAUUAGCUAUCUUUUUUCAAAUUAGACAGAAAAAAAUUCUUGACACUAUUUAAUUUCAGUGCUAGUGAGCAGAUGUUUUAGGGUGCAAGAGCCAUGUUGCUAUUUCAGUUAUGAUGUAAUUAAGCAACAACUGUCUGGCCUGGGUCUACUUCGGUCCCCUUUGCAGGUCAGUUGCUUGGUGUUUCUUUGUAAACCAGAAAAAACUGAGCAAAACAUUCAUUCAUGUAGCUGUAGCACCAAUUUGCUGGCAUCAAUAUUAUGGUAAGGAAAUGUGUUUUUGAACAUUAGCCUAAUAAGCUCUUUGCUACUGCUAUGGUAAGAUAUCAAAUGAAAAACCUCUGUAAAACAUUUCCAGGUUUUUUCUUUCUUAUCACAAUAUCAUUUAAUUAUGCCACAUAUUUUAUUAUACUUACAUAUUUUAACUUUGUUUCUUGUACUUGAGUUCAUUUAAGUAUAAUAAAAUUCAGAAAUUUUUACCAUCUCCUGUUGUCACUUAAAGGGAACUUUUUAUGCCUACCAUUCAUCAGAUUGAAUGAAAAGUAGAGUAUUUGAACUUGUAUGUUUUGUGUGUGUGUGUACGUGCAUACACACAUACACAACCACAGUUUUGUAUCUAUAUAGGAAUAUGGCAGCAUGAUGAGGUAAAAUAUGAGAAACUAUGUUUCAAAGAAAGGUUCUGAGAAAGACUGCACAAAGCCAAUUAUUCUGUGAACAGAAUAUUCUUGAACAAGGUUCUUCAACGCUAUAAACUUCAAAGUCUUUGUCAGUUGGAAAUAAUACUGACUUCCCUUUCAGUAUUUUUAGAAGUUACAUAUGUUUUGAUGAAAAAAUAAAUUGGAUAAAAGUACUUAGUGAGAUAUAAAGUUAGACCUCAUAAUUAAAAAUAUAAUGAAAAGAUAGCCUGAAAAUGGCUAAUUAAAGAAAUUAUAUAAACACUCCAAUCAUAUAUCCUCACCUGAGAAACAAUGCACCUUUUUUCAGAAGAAGCUGAACUACUUUAUCAUGUCCAUUCUUUGCUGCCAGAUGGAGAGGAGUCAUUCCAUGAAGGUCACCUUCAUUCAGAAGCCUCGUAUCACUUAUGUCUUGUAGGAGCCUCUGACAGGUAUUGAUACGCCCAUAACUUGGAAAAAAUUAGGUUUCAUAUUUUCAAGGCAAAUAUUAAACAGAAAGAAGACAUGUUCAUACAUUGCUAGACUGACCCUUACCUGGCUGCAAAAUGCAGAGGUGAUUUCUUAUCUUUGCUUUUGGAAUGAAUGGACACAUUAAAGCCAAGUAGGUUAUUUACAGAACCAGGGCCCCCCUGUCUACAUGCAUAAUGUAGAGGAGUACACCCAUCGUUGUCUUCAUCCAUUACCAGCUCUUUGAUCUGUUGCAUCUAUAGGAAAAAAUUAAUAUCAUACAAAUAACUCUGCUAUUAUGCUAAUAUGAUGGUUUUCAAACUAUUCUGUAGGAAAAUAUUUUCCAACAAGGGUCAAUAUGUAUUCCUUGGGGCCAAAAUUGUAAAUAACCUAAAGGAUUUGAGAGUAAUAUAAAUAUGAAUGAAGUUGAAUGCUCUGUCUUCAUUUAGUGUACAUUACCAUAUUAGUGUACAUUACUGUAUUAAAGGAUCUGAGAGAUCAUGCCAAUAGGAAAAUGUACUUAACAUUUUUAACUCAGCAUUUUUCAAAUAUAUUUGAUCAUGGCCCUUCCCUCUGCCCCUCCUCUUAUUUCCUCCCACCCCCAAAUAACACCCAACAGCUUCAUGUUAAUAUGUUCUGUUAGGUAAAAUGGAUGGGAUGUAAACAUUAGGUUUAUUUUAUGUUUUAUAUGUAUAGUAAAUAAAAAAUGAAUGA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications