SNORD3D: SNORD3D is a dysregulated U3 small nucleolar ribonucleoprotein gene that is associated with age-related immune dysfunction, G0/G1 to S phase transition, oxidative-/ER-stress, and the pathogenesis of Alzheimer's disease [PMC9359077]. In a study investigating the ceRNA network, SNORD3D was found to be one of the 12 lncRNAs involved [PMC7859920]. Treatment with SL resulted in the up-regulation of SNORD3D and other genes involved in RNA processing and translation [PMC4039240]. SNORD3D was also identified as one of the four snoRNAs among 39 genes associated with early-response, stress-response/immune genes, haemoglobin, and breast cancer progression [PMC4818440]. In terms of immunotherapy response in patients with esophageal adenocarcinoma (EAC), SNORD3D was found to be a risk factor for unfavorable responses [PMC9751999]. Additionally, SNORD3D was identified as one of the top dysregulated snoRNAs in a study investigating Upf1 silencing [PMC7415794]. However, there were no significant differences in the expression of SNORD3D between hepatocellular carcinoma (HCC) tissues and pair-matched normal liver tissues [PMC7415794]. References: - PMC9359077 - PMC7859920 - PMC4039240 - PMC4818440 - PMC9751999 - PMC7415794