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hsa-mir-1266: Hsa-mir-1266 is a microRNA that has been found to be related to prognosis in various studies [PMC6151886]. It is part of a five-miRNA signature that includes hsa-miR-203, hsa-miR-424, hsa-mir-1293, and hsa-miR-4772 [PMC5955976]. The expression levels of hsa-mir-1266 have been found to be associated with the MTHFR gene and its 3'UTR region [PMC4505847]. Specifically, the MTHFR 2244 A → G substitution has been shown to increase the binding activity of hsa-mir-1266 with the MTHFR 3'UTR [PMC4505847]. Hsa-mir-1266 has also been implicated in gastric cancer, with decreased expression observed in gastric cancer tissues [PMC5073992]. In addition, it is part of miRNA cliques and has been found to regulate target mRNAs related to neuronal development and neurodegenerative diseases [PMC3878884]. Overall, these studies suggest that hsa-mir-1266 plays a role in prognosis and gene regulation in various diseases and conditions.
mRNA interactions
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