Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
ssc-mir-195: Ssc-mir-195 is a highly expressed microRNA in human pluripotent stem cells (hpiPSCs) and is located in the same genome loci as ssc-miR-497 on chromosome 12 [PMC4934789]. In hpiPSCs, ssc-mir-195, along with other microRNAs such as ssc-miR-106a, ssc-miR-363, ssc-miR-497, ssc-miR-146b, ssc-miR-92b-5p, ssc-miR-20b and ssc-miR-935, were highly expressed compared to mpiPSCs [PMC4934789]. Ssc-mir-195 and other microRNAs such as ssc-miR-20b, ssc-miR-128, and sccmi-R3715p were found to regulate the cell cycle and Neurotrophin signaling pathway through their corresponding target genes [PMC4934789]. Additionally, the P53 signaling pathway was regulated by microRNAs including sccmi-R20b and 497 through targeting specific genes [PMC4934789]. In a study on miRNA expression in pigs' lungs during infection with PRRSV (porcine reproductive and respiratory syndrome virus), it was found that miRNAs including mir195 were significantly down-regulated at 3 to 7 days post-infection compared to 0 days post-infection [PMC5381705]. Furthermore, mir195 has been reported to induce postnatal quiescence of skeletal muscle stem cells [PMC6737989]. These findings highlight the importance of mir195 in various biological processes.
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset