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hsa-mir-4463: Hsa-mir-4463 is a microRNA that has been identified in human HEK293 and HeLa mitochondria [PMC8362354]. It is one of four known miRNAs, along with hsa-miR-4461, hsa-miR-4484, and hsa-miR-4485, that can be aligned to the mitochondrial genome at specific positions [PMC6792129]. Hsa-mir-4463 has been found to be involved in the downregulated miRNA network and may regulate the expression of DSCAML1 and LDLRAD1 by interacting with lncRNA ADAMTS9-AS2 [PMC6558619]. It aligns to a specific position on the mitochondrial genome corresponding to the ND5 gene [PMC3439422]. Hsa-mir-4463 has also been shown to potentially target BCAS4 and SHISA7 in AD-related neurofibrillary pathology [PMC8899724]. In addition, it has been identified as one of the top five unregulated miRNAs in a study [PMC8973762]. Furthermore, it has been found to be exclusively downregulated in gallbladder cancer patients with long-term survival compared to those with short-term survival [PMC7238852]. Hsa-mir-4463 is also one of the miRNA binding sites for hsa_circ_0089172 [PMC6579753].
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