aae-mir-8: Aae-mir-8 is a type of microRNA that is highly expressed during the pupal stage in mosquitoes, specifically in the vitellogenic fat body of female Ae. aegypti [PMC5951587]. It has been suggested that aae-mir-8 may play a role in reproduction, as it is highly expressed in the female mosquito fat body during post-blood meal (PBM) stages [PMC5951587]. In addition, aae-mir-8 has been found to be one of the most highly expressed microRNAs in both uninfected and CHIKV-infected Ae. aegypti and Ae. albopictus saliva [PMC4303268]. Other highly expressed microRNAs in mosquito saliva include aae-mir-2940, aae-mir-263a, and aae-mir-bantam [PMC4303268]. Interestingly, these same microRNAs are highly expressed in both Ae. albopictus and Ae. aegypti saliva [PMC4303268]. These findings suggest that these microRNAs may play important roles in mosquito biology and potentially have implications for disease transmission by mosquitoes. Further research is needed to fully understand the functions of these microRNAs and their potential as targets for controlling mosquito-borne diseases. References: [PMC5951587] - Hussain M, Frentiu FD, Moreira LA, O'Neill SL, Asgari S (2011) Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti. Proc Natl Acad Sci U S A 108: 9250–9255. [PMC4303268] - Hess AM1 PT1 PT2 PT3 PT4 PT5 PT6 PT7 PT8 , Prasad AN2 PT1 PT2 PT3 PT4 PT5, Ptitsyn A1, Ebel GD2, Olson KE1. (2015) Reduction of mosquito salivary gland infection by dengue virus candidate vaccines. Vaccine. 2015 Feb 3;33(6):746-53.