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Homo sapiens (human) hsa-miR-1827 URS000056215C_9606

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hsa-mir-1827: Hsa-mir-1827 is a microRNA that has been identified in various studies. It has been shown to decrease luciferase reporter activities in a dual-luciferase reporter assay, along with other miRNAs such as hsa-miR-326, hsa-miR-330-5p, and hsa-miR-623 [PMC8824756]. Hsa-mir-1827 is part of a ceRNA network that includes other miRNAs such as hsa-miR-3191-3p, hsa-miR-4731-5p, and hsa-miR-598-5p [PMC8611860]. It has been found to regulate the expression of MYCL1 and MYC [PMC4229095] [PMC7596315]. Hsa-mir-1827 has also been implicated in tumor suppression in lung carcinomas and is involved in cell migration, invasion, and apoptosis [PMC7596315]. Additionally, it has been identified as one of the most expressed miRNAs along with hsa-let7e5p, hsa-mir7977, hsa-mir1555p, and hsa-mir1865p [PMC9429819]. The length of the miRNA varies from 17 nucleotides to 27 nucleotides [PMC9316571]. Hsa-mir1827 has also been studied for its binding sites on target genes such as RBX1 and CRKL [PMC5771341]. Overall, these studies highlight the importance of hsa-mir1827 in various biological processes.

mRNA interactions 1 total

Genome locations

Gene Ontology annotations

Sequence

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UGAGGCAGUAGAUUGAAU

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This sequence is found in 1 other species

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