mmu-mir-298: Mmu-mir-298 is a microRNA that has been studied in various contexts. In a study, it was found that mmu-mir-298 was up-regulated in the colon and down-regulated in the forestomach [PMC4209037]. Another study showed that mmu-mir-298, along with mmu-miR-141 and mmu-miR-375, were released into the serum with disease progression [PMC8855122]. Exosomes were found to play a major role in the transfer of mmu-mir-298 [PMC4496353]. The transfer of mmu-mir-298 from endothelial cells to tumor cells was observed, although HCT116 cells showed reduced transfer levels [PMC4496353]. Mmu-mir-298 has been shown to have potentially downregulated target genes in the ileum [PMC3084815]. It has also been found to directly act on the 3'–UTR of CYP3A4 [PMC4629097]. It is important to note that there are differences between mature hsa-miR-298 and mmu-mir-298 sequences, highlighting the need for human systems for verification [PMC8758483]. Mmu-mir-298 has also been shown to influence CYP3A4 expression along with miRNA27-b [PMC8972743]. The expression of HSA-miR-299-3p and mmu-mir-298 is up-regulated in SLE and down-regulated in ITP, potentially serving as a biomarker for differentiation between these conditions [PMC9096216]. Mmu-mir-298 has also been observed to target IKKi/IKKϵ when expressed during SA1 and SA2 infection [PMC4114167]. In various experiments, mimics of mmu-mir 291–3p, mmu-mir-25, mmu-mir-302, mmu-mir-292-5p, mmu-mir-106a, mmu-mir-21, and mmu-mir-298 were used [PMC3422281].