Homo sapiens (human) cancer susceptibility 18 (CASC18)

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Homo sapiens (human) cancer susceptibility 18 (CASC18) URS000055ECA4_9606

2,521 nucleotides
4 databases (ENA, GeneCards, HGNC, RefSeq)
Found in 0 other species
12 publications
lncRNA

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CASC18: CASC18, a long non-coding RNA (lncRNA), is located in a cancer predisposition locus at 12q23.3 and exists in four splice variants (A, B, C, and D) [PMC5774710]. Recent research has demonstrated that the regulation of CASC18 is dependent on the binding site of miR-20a-3p [PMC8349069]. Specifically, the luciferase activity of TGFB2 3′UTR-mut was unaffected by miR-20a-3p inhibitor and CASC18 knockdown, indicating that regulation occurs in a miR-20a-3p binding-site dependent manner [PMC8349069].

Genome locations

Gene Ontology annotations

Sequence

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AGCUGAUUUUCUGACAGCCCCUUCUCCUCUCCUCACUGGAUAUCCAGUUUCCAGGGUCUGUGUGUGGUGGGAAGCAAACUGGCCUGAGGUUCCAUCCACUGGUAGAAAUGACCCCAAAGACUUCCCAUGCAGGGAGGGCAAAGAAGAAAGUGCUUUGGAAUGGAGAUACCCCUUUUCCUCCUCCUGAAUGUAUCAGAGUUAGUUAUCAAUGCUGACUGAGUGUGCACUCUCCUAGACACCAUGGGGAGAGGCAGAAGAGGAAACCAGAUAUGAUCCUUCUUCUUGGGACUCUCCUGACCUAGGAAAAGAGACAGAUGAAUGCAGAUAACUGAGUCUAUAUACAGAGACUGCCACAAGCUCACACUUUACUGAAUGUUCAGACCUAGUCAUACAUCCUAAGGGCAUUGUUGGAAGCUUCUGGAACUAAGUCUCUGGGGAUUUGAAUCAACUCAGAAGACUGACUCAUUCACUUGGCUGUGGAGGCUGUUCCAGAUAUUAGGAGCUAUGUAUGUGGAGCCCCGGAUUUGGGCCAAAAGAUGCAUUUGACUGGAGAGAAGGGAUUGAGAUUUGAGCAGUUGUUGGACAACACAGAAAUGAAACAGCCGUAGCAAACUUGCCUGCCGUGAUUUCUCUGCUGAGAUAAUGGGACUUUUCAGACUCCCUGUAACUGAGAUCUAGAUAAAAAGAGACGUCUGGAAAAAAACUGGUCCCAAUUGUCGCUUGGCUUUGCUUUCAUAACUAUCUGAGUGUGGCAUAUGUCAGACUUUGAAAUGCUGGGUCUCUUGGAAAUACAAAUACCAUCUGGGUCUGGAUAAUUCCCAGAAACCUAGGCUACUCAGUAGGAAAUGAGGAGCUGGAAACAUAAUACCGAGACCAGGGGCUUGUCCUUGGGCCACCCUGUCUCGUGUCCUGGACACAGUCACAUGACUCGUACAGAAAAUGUCACUGGGAAGACACCAUAAGGCUCAUCUUUUCACGACACAGUGACCUCUGUUAUGGACAUCUUGAUUUCUCUUUGAGAAGCCAUCCCUCCCCCAGUGUGUAUAGUCUAGCAGCCAAGUCCGCCUUGCCUCUGGCCAAGGGCAGCCUGAAACUCAAACAGGGCCCAUCCCUUAUCCCUGGAUGGAAAUCUUGAGCAGAGUGCCUGACGGGACUGAAGAUGGCUGAAAUUCCAGCAAGCAGACAGUGGUUCUCUGAAGAGGCUCCCCUCCGCCCACACCCAUGAGUGUCUGCUCCCCAGAUGCUCCAAUCCUACUUCUCCAGCUUUACCUUCUGUUCCAUAAGCUGCUUCAUUUUCUUUCUCCAAAUCCCUCUUUUGCUGGUUGGACAAAGAUUGUUUCUGUUGCCUGCAAUCAAAUAACCCAAAAGGAUGAACAGGUGAAAUCAUAAACAUACUUUUAAGUGCCUGGAAUAUGCCUGCUUCUGUCCAUCUUUCAACCCACUUGCAUCAGAAGCCCCCUUGGAGGAUGAGAGCCUGUCCUGUGAACCAUGGUGGUUCAGAGUGGAACACAGCAGAGUGUGGAACACCAGGAAUUUAGAGCAAUCAGUGAAAUAUGAUGUAGGCCUCUAUGUCAGAAAAAUUACUAAUAAGCAGUUGAUUAUUAGUAAUCAAUAAUAGCCUUCCCAUUUUAUAUCGAGCACAGCAGUCAGCAUGUUAAAAACAAGGACUGCUGGACACCAGCUGCGAUGAAAUGCUUUAUCAGAGGACGGCCCUUGAUGUCUAUGUCCAUUUGCAAGUGCGGCAUUAAUUACAAGGCUGGUUUAAGUAUAAUCAGUAAGUUUAUAUGCUGGAUGCUCAAGAUGAUUUCUGGCUAAACAUGGAAUUUCUAUUUCUAUUUUCCUUAUGUUAAAAGCCGGAACAGCAAAAUGUAUUCCUAAUGUCACUAUUAUGACAUUUACAUCCCGAAAAGUUGCAGUAACUGAUCAAUACAAUAGUGGAAUGCCUGGAAACCUGUUCCUUUUUUGCUAAAAAAAGGAGGGCACUUUUUAUGUCUUUGAUGUGAAGUUCAUGUUCUUUGACAGUGAUUGAUGGAAUAUGCUACAGAAAAGGCUGAUUACAUUUUACUAGAGAAGUAAAAAAGAAAUGCAGGAGAAUCCCACAGCUCUGGGAUUGAAUGGAAAGCAAAGGAGGAGCUCCUCUAGGGGGCUAUGGGAUGCCUCUGUGUAGCUAUUGAAUCUCUGGGGCCAUGGAUGAGAAUUUGCUUGGUCAGUAGGUCAGCAUUCAAGAGUAUGGGCUGGAUGCAGAGUAAACGACCUGCUGAGAGUAAUGGCCACUGCUUUACUUCUGUCUUCAAAAUCCUGAACAAGCUCCUCUUUUGGCCAACUCUAACCUGGAACCAUGCAGAUUAGGAAGAGAAAGAGAAGUGGAUUGUGAGAAAGAUUUUAGCUUGGUCAAGUUGAUAACGGGAUGAUUCAGAAGAAUGCAACCCUUAUCAACUAGGUAUAUCUCUUUUUUCCUACAUUUAUUGUCCAAAUAAAGCAAAAUCAUGCUUUCACCUGCCUGAAAAAAAAAAAAAAAAAA

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Publications