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rno-mir-184: Rno-mir-184 is a microRNA that has been found to be associated with heart failure (HF) and the development of thecal hyperandrogenesis [PMC4978447] [PMC3682887]. In a study on failing myocardium, rno-mir-184 was identified as one of the most significantly differentially expressed miRNAs between HF and control groups [PMC4978447]. Additionally, rno-mir-184 was found to be upregulated during the development of heart failure [PMC4978447]. In another study, rno-mir-184 was significantly higher in LNCs (luteinized granulosa cells) compared to 3T3 cells [PMC9398820]. Furthermore, rno-mir-184 was dysregulated in GHS (growth hormone secretagogue) rats and showed one of the largest positive fold changes in expression compared to control rats [PMC4824905]. The downregulation of rno-mir-184 has also been associated with promoted thecal hyperandrogenesis [PMC3682887]. Additionally, rno-mir-184 has been identified as one of the most abundantly upregulated miRNAs in prostate tissues when comparing different conditions such as CAR (castration-resistant prostate cancer) versus BC (benign prostate hyperplasia) and CAR versus NS (normal prostate tissues) [PMC6628738]. Overall, these studies highlight the potential role of rno-mir-184 in various physiological processes and diseases.
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