Mmu-Mir-145: Mmu-mir-145 is a microRNA that has been studied in various contexts. It has been selected based on its high or low signal intensity in microarray analysis, as well as its potential role in lung pathology [PMC3030602]. Differential analysis of mmu-mir-145 has shown down-regulation during ovarian growth, indicating its involvement in cell proliferation [PMC4499447]. Similarity in sequence and function has been observed between mmu-mir-145 and hsa-miR-145 [PMC3926854]. Mmu-mir-145 has also been chosen for validation based on its target genes, which are relevant to inflammation and cancer [PMC4062425]. It is enriched in murine cardiac progenitor cells and during cardiogenesis [PMC7936154]. In genetically obese mice, mmu-mir-145 exhibits increased hepatic expression [PMC7936154]. Mmu-mir-145 is one of the top differentially expressed miRNAs in abdominal aortic aneurysm (AAA), with significant downregulation observed [PMC7377859]. It maps to chromosome 7 and exhibits a high LOD score, with each eQTL explaining 21% of the observed variation on average [PMC3130556]. In a study analyzing the expression of mmu-mir-145 and mmu-miR-483* in mice under different diets, a negative correlation between the two miRNAs was observed in the control group but was dampened with CDAA treatment [PMC5058762].