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Homo sapiens (human) long intergenic non-protein coding RNA 269 (LINC00269) URS000050E9EC_9606

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LINC00269: LINC00269 is a long intergenic nonprotein-coding RNA (lncRNA) [PMC7359110]. It is located within a 616 kb fragment that also contains the genes PJA1 and FAM155B [PMC7359110]. LINC00269 has been shown to impair migration and invasion capacities in a choriocarcinoma in vitro model [PMC5539301]. In osteosarcoma, LINC00269 is one of the 13 lncRNAs (along with DSCR8, IGF2BP2-AS1, MIS18A-AS1, RUSC1-AS1, FGD5-AS1, LINC00307, LINC00355, LINC00482, LINC00544, LINC01545, SNHG17) that have prognostic value [PMC8176230]. In high-risk osteosarcoma patients, the expression levels of LINC00482 SNHG17 IGF2BP2-AS1 RUSC1-AS1 LINC00544 and LINC00307 are higher compared to low-risk patients [PMC8176230]. On the other hand FDG5-AS1 MIS18A-AS1 LINC01545 and DSCR8 are expressed at lower levels in high-risk patients [PMC8176230]. These findings suggest that lncRNA expression levels can be used as prognostic markers in osteosarcoma.

Genome locations

Gene Ontology annotations

Sequence

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CUUCUCCCCCGCCAGCUCGCCAGCUCGGGAGCUUCUUGAGAGCAGGGUCCAUGGCAGGCUUUGCUCACCAUUGCGUGGCUCCAGGCUCAUGUUUCCCUCAGACUUUUAUUCAUUCAAGCAGCAUGUAUUGGAUACCUACUAUACAACAAGCAUUGUUCUAGGAACCAGGGAUACAGUGGCAAAAAUGACAAGCCAUAGACCCUGCCCUCAUGAAACUUCAUGUAGAGGAGACAUACAGCAGAUCGAAUCCUAGACUCACUGUCUGAUCCGGAAGGCACUUUAAUCAUGCCUAAGAGCCUGGAGAUUUAUAAAGGAAGCUGUAACUGGGAAGAAUCCGGCCUGCUGGGAAGCUGCUUCUCCCAGGGUCUUGCUCUAUUACCCCGAGUGGAGUGGAGUGGUGCCAUCUUGGCUCAUUGCAUCGUUGACCUCCCGAGCUCAAGUGAUCCUCCCACCUCAGCCUCCCACUUUUCGGGACUACAGGCACACACCACCACAGCCAGAUGGAGUCUCACUCUGUUGCCCAGGCUUGAGUGCAGUGGCACAAUCUCGGCUCACUACAACCUCCGCCUCCUGGGUUCAAGCAAUUCUCCUGUCUCAGCCUCCCAAGUAGCUGAGACUACAGAGGCAUGCCACCACACCAGGCUAAUUUUUGUAUUUUCAGUAGAGACGGGGUUUCACCACGUUGGUCAGGCUGGUCUCAAACUCCUGACCUCAGGUGAUCCACCUGCCUCAGCCUCUCAAAGUGCUGGGAUUACAGGCGUAAGCCACAGUGCCCGGCCCAAAAGUUGCUUUCUCCAACUUUUGGGCUGAACUCUGUCUCUUUGUGGCUUCCAUCCAUUGGUCACAGUGCUGCCUCUGGGGGCCACCUAAGCUCUGUCUUCUCCCUCUGCCCUCCAACAGCUUCUUAGAGGUCUGAAGCAUCACCAUAGCCAUAACCCCUGAGUCUUCUCCAAGCAAAACAACUCCACUUCCUUCAACUGUUCUUCAUGAGACCAGGGCCCCCGCUUUCUCCACAGCAUGCUUUUGCCUCCCUGGUCAUGCUCCAGUGUGACUCUGGUACCCUUAAUAUGUGGCACACAGAGCUGACACCAUAUUCCAGGGCAGUCUGUCACCUCCUUGUUCUUGAAACUUUACUUCUAUACUGCCUACAGAUGCAGCUGAAGGUUCCAUGGAUGUAUUUGGUCAGACCAUGCAUAUGACAGUCACCUCCUCACCUCUGCUCCUUGCCCUCUCACCUGGUUCCCCCUUGCCAGCCUACAUUUGAGGACUGGAUCCAAGAGCAAGACCUAACAUUUCUCCCUGUCGUAUUUACUUUGUAAGCUUCAGCCCCUCCUUCUAGUCUGUCAGGAAUGGGAAUGUUUUUGAAAACAGACUCUGAAAGCCAAUGAGAUGUGCUCCUCCUGCCCACAGUUGGACCCAGGCUCCAUAUUUGAUCAGUGAACAGCCACGUCCGCACAUGUGCCACAAGGCAUUUGUCUGCAAAUUCAUCCGGAGACCUUGACAGAUGCCUGGAGGUCAGAAAUCAGCCUCCUCUAUGCUGCCAUGUGGCCCCAGGAGCCUGAAGGAAACACCAAGUACAUCUAGAAGUUGAUGGUUGACCGAUGGGAGAGGGGGCAAGAUGCCAGUCACUCAGUCAGCCAACCUUUCCUGAAGAUUGUUGGAGGCUCCAAGUGACAUAGGGGAUAAUGCAGAGAACAUUCAGAGACAUCAUCUACUGCCUGUGCGCUCUGGAAGUUUCUAGUCUCACAAAAAGGAAGACCAGGGAGGCCCUUAAGAAAAUAUAGCAGGCUGAAUAAUAUCCCCCAAAGAUAUCAGGUCCUAAUCCCUGGAACCUGUAAAAGUUACCUGAUUUGGAAAAAUGAUCUUGGCAGAUGUGAUCAAGUUAAGGGUUUCUAAAUGCAAUCACAUAAGAGGGAGGCAGAGGAGACUUGAAACAGAUGGAAAAAGAAAAGAAAAGACCACGUGACCAUAGAGGCAGAGAUUGGAGUGAAGUGGCUACAAGCCAAGGAAUGCUGGCAGCCACAGAAGCUGGAAAAGACAAGGACCAGAUUCUCCCUUAGAGCCUCUGGAAGGAGCAUGGCCCCAUCAACACCUUGAUUUUGGCCCAGUGAUACUGGCUUUAGACGUCUAGCCUCCAGAUCCGUGAGAGAAUACAUUUUUGUUUUCUUCAGCC

Taxonomic tree

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Expression New Publications