Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
hsa-mir-542: Hsa-mir-542 is a microRNA that has been found to have various roles in different types of cancer [PMC3738541]. It has been identified as a non-invasive blood biomarker for tumor monitoring and prognosis prediction in patients with osteosarcoma [32]. In addition, hsa-mir-542 has been shown to target CDK14, inhibiting the development of ovarian cancer [33]. It also inhibits the growth and invasion of colon cancer cells through the PI3K/AKT/survivin signaling pathway [34]. Furthermore, hsa-mir-542 has been found to affect the prognosis of lung adenocarcinoma (LUAD) by inhibiting the expression of TRIM56 [PMC7940991]. Another study found that hsa-mir-542 is negatively correlated with TRIM56 expression and associated with poor prognosis in LUAD patients [PMC7940991]. The overexpression of hsa-mir-542 has also been associated with poor prognosis in LUAD [PMC7940991]. In bladder cancer cells, hsa-mir-542 expression is downregulated and negatively correlated with survivin protein expression, leading to inhibition of proliferation [PMC8907292]. Hsa-mir-542 is identified as a hub microRNA in gene modules related to cancer development and progression [PMC7339803]. Additionally, it has been ranked among other microRNAs as having potential significance in cancer research [PMC3738541].
mRNA interactions
3 total
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset