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hsa-mir-592: hsa-mir-592 is a microRNA that has been studied in various contexts. It has been found to show correlation with monosomy 3 tumors [PMC7958896]. In breast cancer samples, hsa-mir-592 expression was significantly higher compared to healthy samples and was found to regulate the extrinsic prothrombin activation pathway [PMC6208346]. Additionally, hsa-mir-592 is part of a group of 9 miRNAs that regulate the extrinsic and intrinsic prothrombin pathways [PMC4512830]. In a study comparing urinary bladder cancer patients and a control group, hsa-mir-592 was one of the microRNAs that showed statistically significant differences in expression [PMC5650163]. It has also been included in specific probes used for amplifying miRNAs in RNA samples [PMC8533892]. In terms of tumor metastasis, hsa-mir-592 was found to be upregulated in metastatic tumors compared to primary tumors [PMC7140886]. Furthermore, it was observed that hsa-mir-592 and other miRNAs were more highly deregulated in patients with high-grade disease compared to those with low-grade disease [PMC6423615]. Additionally, hsa-miR-599 and hsa-mir-592 were proposed as potential regulators of other mRNAs related to pRS [PMC8176413]. Furthermore, it has been suggested that hsa-mir-592 may indirectly affect TBEV replication [PMC9167876]. Finally, Kaplan-Meier analysis showed that hsa-mir-592 could effectively distinguish high-risk and low-risk groups in terms of prognosis [PMC9695425].
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