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mmu-mir-705: Mmu-mir-705 is a microRNA that has been found to be directly correlated to angiogenesis [PMC6247691]. It is one of the top-rated miRNAs that have been identified to have vital regulatory effects in the network [PMC6247691]. Mmu-mir-705 has also been shown to target genes in the PI3K/Akt signal pathway related to ischemic cerebral angiogenesis [PMC6247691]. In addition, it has been observed to be involved in a large number of gene ontology annotations [PMC6247691]. Mmu-mir-705 has been detected using LNA-modified detection probes labeled with -dATP [PMC4103684]. It has also been detected using radioactive locked nucleic acid (LNA)-based ISH with unlabeled detection probes [PMC4103684]. Mmu-mir-705 has been found to be a negative regulator of osteoblast differentiation by targeting HOXA10 and Runx2 genes, and its expression is enhanced in ovariectomized mice through the TNF-α activated NF-kB pathway [PMC7116989]. Furthermore, it has been predicted to be involved in a network related to mmu_circRNA_21040 and its target genes have also been identified [PMC9574125]. Overall, mmu-mir-705 plays important roles in angiogenesis, osteoblast differentiation, and gene regulation.
Genome locations
Gene Ontology annotations
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