bta-mir-136: Bta-mir-136 is a hub miRNA that is involved in various biological processes [PMC6637853]. It is expressed at a higher level in Wagyu cattle compared to Holstein cattle [PMC6637853]. In cows with negative energy status, bta-mir-136 is one of the miRNAs found on chromosome 21 [PMC6731312]. Humans also have identical miRNAs to bta-mir-136, such as hsa-miR-136 [PMC8787201]. The RTL1 gene is targeted by the greatest number of miRNAs, including bta-mir-136, in both humans and cattle [PMC8787201]. The nucleotide sequence of bta-mir-136 has full complementarity to 13 mRNAs of human genes [PMC8787201]. Bta-mir-136 has been detected in bovine milk and colostrum [PMC8787201]. Overall, bta-mir-136 is a hub miRNA that plays a role in various biological processes and shows differential expression between cattle breeds. It also has similarities with human miRNAs and targets the RTL1 gene. Additionally, it can be found in bovine milk and colostrum.