rno-mir-203: Rno-mir-203 is a microRNA that has been studied in the context of ischemia and acute kidney injury (AKI) [PMC7943304]. KEGG and Wiki analyses have identified several functional categories modulated by rno-mir-203, including metabolic pathways, mRNA processing, cancer pathways, ubiquitin-mediated proteolysis, MAPK signaling, TGF-β signaling pathway, and TGF-β receptor signaling pathway [PMC4178201]. Rno-mir-203 is predicted to have 386 target genes [PMC4178201]. Methylation-specific primers were designed to study the methylation status of rno-mir-203 promoter [PMC4950120]. The downregulation of rno-mir-203 in AKI may be due to its methylation status [PMC4950120]. The levels of rno-mir-203 were significantly reduced in H/R or antimycin A-treated cells compared to normal cells [PMC4950120]. Rno-mir-203 may attenuate Aldosterone-induced cell apoptosis by inhibiting death receptor and mitochondrial apoptotic signaling pathways [PMC4950120]. Kim-1 has been identified as a direct target gene of rno-mir-203 in NRK52E cells through luciferase reporter assays [PMC4950120]. The levels of rno-mir 203 were significantly increased when I/R mice were treated with spironolactone compared to untreated mice [PMC4950120].