mmu-mir-710: Mmu-mir-710 is a microRNA that does not have an annotated homologue in the human microRNAome and its mature sequence does not appear to be conserved [PMC6910689]. In a study, it was found that mmu-mir-710 does not harbor the predicted target binding site for STIM1/2 or Orai1 and therefore, did not affect SOCE [PMC5685687]. The study also showed that mmu-mir-710 lacks the predicted binding site in STIM2 or Orai1 3’UTR region and did not influence their transcription [PMC5685687]. However, mmu-mir-710 was found to have 508 predicted targets related to cell cycle, cytoskeletal remodeling, invasion and migration, and stemness [PMC6910689]. In murine metastatic breast cancer cells, mmu-mir-710 was shown to have a broad-based and significant effect [PMC6910689]. The study suggests the possibility of employing miRNAs like mmu-mir-710 for therapy since it is not naturally present in the genome but has potential targets in both murine and human systems [PMC6910689]. Additionally, it has been shown that mmu-mir-710 enhances the differentiation of murine embryonic stem cells [PMC6910689]. References: [PMC5685687] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685687/ [PMC6910689] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910689/