hsa-miR-548i: Hsa-mir-548i is a member of the hsa-mir-548 family of microRNAs. It has been shown to be downregulated by greater than 16-fold in basal cell carcinomas (BCCs) [PMC8357504]. The hsa-miR-548 family, including hsa-mir-548i, has been found to regulate cancer processes at both the gene expression and single nucleotide polymorphism (SNP) level [PMC8357504]. In a study on heart failure, hsa-mir-548i was identified as a potential novel biomarker [PMC8256614]. In patients with severe asthma, hsa-mir-548i was found to be differentially expressed between those treated with oral corticosteroids (OCS) and those not treated with OCS [PMC9864670]. Hsa-mir-548i is involved in the regulation of the "PIP3 activates AKT signaling" pathway in both granulosa cells and mural granulosa cells [PMC8501715]. It has also been detected in other body fluids, such as follicular fluid [PMC8501715]. Hsa-mir-548i is one of several miRNAs that are highly expressed and exhibit increased expression in certain conditions, such as cancer [PMC6884461]. In patients with chronic obstructive pulmonary disease (COPD), hsa-mir-548i was downregulated along with other miRNAs in different patient groups [PMC9889280]. References: [PMC8357504]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357504/ [PMC8256614]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256614/ [PMC9864670]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864670/ [PMC8501715]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501715/ [PMC6884461]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884461/ [PMC9889280]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889280/