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Hsa-Mir-486: Hsa-mir-486 is a microRNA that has been studied in various contexts. In a study evaluating its ability to differentiate between healthy children and children with congenital heart disease (CHD) or autism spectrum disorder (ASD), hsa-mir-486 levels did not show a significant correlation between these two populations [PMC5828434]. Another study found that overexpression of hsa-mir-486 enhanced fusion capacity in control myoblasts, but was not powerful enough to rescue the effect of TNF-α [PMC4325962]. In patients with ovarian cancer, hsa-mir-486 was found to be part of a miRNA signature associated with prognosis [PMC8148489]. Hsa-mir-486 was also identified as one of the most important miRNAs in differentiating responders from non-responders in a group [PMC7770508]. Furthermore, hsa-mir-486 is located within the last intron of the ankyrin-1 gene on chromosome 8p11's short arm [PMC9132198]. In another study, hsa-mir-486 was found to be downregulated in a group of miRNAs associated with colorectal cancer [PMC5823624]. These findings highlight the diverse roles and associations of hsa-mir-486 in different biological contexts.
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