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rno-mir-486: Rno-mir-486 is a microRNA that has been studied in various contexts. In a study comparing different groups, the expression levels of rno-mir-486 were found to be significantly higher in a polycystic ovary syndrome (PCOS) model [PMC5637260]. Another study using sRNA-seq found that rno-mir-486 was downregulated in injured samples compared to normal samples [PMC9141346]. In the context of spinal cord injury (SCI) recovery, rno-mir-486 was identified as one of the candidate miRNAs involved [PMC7339738]. However, there was no significant difference in the expression levels of rno-mir-486 between different groups in another study on SCI recovery [PMC7339738]. Rno-mir-486 was also found to be one of the most abundant mature miRNAs identified in a study on exercise-induced changes in miRNA expression [PMC5976735]. Additionally, rno-mir-486 has been associated with various diseases such as colorectal disease and prostate and pancreatic cancers [PMC6203938]. Furthermore, it has been shown that rno-mir-486 targets specific genes involved in certain pathways related to disease progression and recovery [PMC7339738] [PMC7023842] [PMC6203938]. Overall, these studies highlight the importance of rno-mir-486 as a potential biomarker and therapeutic target in various pathological conditions.
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