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ssc-mir-370: ssc-mir-370 is a miRNA that has been identified as an important regulator of pig subcutaneous adipocytes and the differentiation process of subcutaneous adipocytes [PMC8834144]. It targets a large number of genes involved in the regulation of fat metabolism and is associated with pathways related to adipocytokine signaling, MAPK signaling, and glucose metabolism [PMC8834144]. ssc-mir-370 has also been found to target genes such as HHAT and GRIN3A, which are important candidates for the regulation of porcine subcutaneous adipocyte differentiation [PMC8834144]. Additionally, ssc-mir-370 has been implicated in the regulation of intramuscular fat deposition and collagen via protein digestion and absorption pathways [PMC9454643]. It has been found to be downregulated in intramuscular adipose tissue and associated with the upregulation of genes such as COL5A3 in pigs [PMC9454643]. Furthermore, ssc-mir-370 has been identified as a regulator involved in precocious sexual maturation traits in HZ boars, targeting the SPATA3 gene [PMC9622794]. It is also involved in regulatory networks related to mRNA-miRNA-lncRNA interactions and mRNA-miRNA-circRNA interactions [PMC8614448]. Overall, ssc-mir-370 plays a crucial role in various biological processes related to fat metabolism, tissue development, and sexual maturation.
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