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Sus scrofa (pig) ssc-miR-103 URS0000476BE1_9823

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ssc-miR-103: Ssc-mir-103 is a member of the miR-103/107 family, which has been shown to attenuate miRNA biosynthesis by targeting Dicer [PMC3770649]. It has been observed that the down-regulation of ssc-mir-103 during myofiber formation and maturation may affect myogenesis [PMC3770649]. Ssc-mir-103, along with ssc-miR-15b, ssc-miR-16, and ssc-miR-221-3p, has been found to have different expressions in the myofiber between lean and obese pig breeds [PMC7552122]. Ssc-mir-103 and ssc-miR-221-3p have also been associated with meat quality [PMC7552122]. Ssc-mir-103 is potentially involved in regulating leukocyte migration and chemokine activity by targeting genes such as CDC42, CXCL12, VEGFD, CCL25, CXCL14, and CXCL16 [PMC8851844]. Ssc-mir-103 is one of the ten miRNAs that have been selected as reference genes in different porcine tissues and breeds [PMC3438195]. It has also been found to be abundantly expressed in LPS-treated PBMCs [PMC7903524]. In tooth development studies, ssc-mir-103 has shown expression in various tissues such as enamel epithelium, dental mesenchyme, stellate reticulum, and different types of teeth at different stages [PMC4696248]. In castrated male pigs, down-regulation of ssc-mir-103 has been observed along with other miRNAs involved in the TGF-beta signaling pathway for fat deposition [PMC3901342]. Among conserved miRNAs expressed abundantly are ssc-mir-103, ssc-let-7a, ssc-miR-140-3p, ssc-miR-199a-3p, and ssc-miR-199b-3p [PMC5815207].

Genome locations

Gene Ontology annotations

Sequence

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AGCAGCAUUGUACAGGGCUAUGA

Taxonomic tree

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This sequence is found in 66 other species

  1. Alligator mississippiensis (American alligator) Ami-Mir-103-P2_3p (mature (guide))
  2. Anolis carolinensis (green anole) Aca-Mir-103-P2_3p (mature (guide))
  3. Ateles geoffroyi age-miR-103
  4. Bos taurus bta-miR-103
  5. Callorhinchus milii Cmi-Mir-103-P2_3p (mature (guide))
  6. Canis lupus familiaris (dog) cfa-miR-103
  7. Capra hircus (goat) chi-miR-103-3p
  8. Cavia porcellus (domestic guinea pig) cpo-miR-103-3p
  9. Cervus elaphus cel-miR-103
  10. Chiloscyllium plagiosum microRNA cpl-miR-103
  11. Chrysemys picta bellii (western painted turtle) Cpi-Mir-103-P2_3p (mature (guide))
  12. Columba livia (rock pigeon) cli-miR-103-3p
  13. Cricetulus griseus cgr-miR-103-3p
  14. Cyprinus carpio ccr-miR-103
  15. Danio rerio dre-miR-103
  16. Dasypus novemcinctus dno-miR-103a-3p
  17. Echinops telfairi Ete-Mir-103-P2_3p (mature (guide))
  18. Equus caballus eca-miR-107a
  19. Gadus morhua gmo-miR-103-3p
  20. Gallus gallus (chicken) gga-miR-103-3p
  21. Gekko japonicus Gja-Mir-103-P2_3p (mature (guide))
  22. Gorilla gorilla gorilla ggo-miR-103 (MIR103)
  23. Gorilla gorilla ggo-miR-103
  24. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-103
  25. Homo sapiens (human) hsa-miR-103a-3p
  26. Ictalurus punctatus ipu-miR-103
  27. Ictidomys tridecemlineatus microRNA miR-103
  28. Lagothrix lagotricha lla-miR-103
  29. Latimeria chalumnae (coelacanth) Lch-Mir-103-P2_3p (mature (guide))
  30. Lepisosteus oculatus (spotted gar) Loc-Mir-103-P2_3p (mature (guide))
  31. Macaca mulatta (Rhesus monkey) mml-miR-103-3p
  32. Macaca nemestrina (pig-tailed macaque) mne-miR-103
  33. Maylandia zebra mze-miR-103
  34. Microcaecilia unicolor Mun-Mir-103-P2_3p (mature (guide))
  35. Microcebus murinus (gray mouse lemur) mmr-miR-103b
  36. Monodelphis domestica mdo-miR-103-3p
  37. Monopterus albus Mal-Mir-103-P2b_3p (mature (guide))
  38. Mus musculus (house mouse) mmu-miR-103-3p
  39. Neolamprologus brichardi (lyretail cichlid) nbr-miR-103
  40. Nomascus leucogenys nle-miR-103a
  41. Ophiophagus hannah oha-miR-103a-3p
  42. Oreochromis niloticus oni-miR-103
  43. Ornithorhynchus anatinus (platypus) oan-miR-103-3p
  44. Oryctolagus cuniculus ocu-miR-103a-3p
  45. Otolemur garnettii oga-miR-103b
  46. Ovis aries (sheep) miscellaneous RNA
  47. Pan paniscus (pygmy chimpanzee) ppa-miR-103
  48. Pan troglodytes ptr-miR-103
  49. Papio hamadryas (hamadryas baboon) pha-miR-103b
  50. Petromyzon marinus pma-miR-103b-3p
  51. Pongo pygmaeus (Bornean orangutan) ppy-miR-103
  52. Pteropus alecto (black flying fox) pal-miR-103b-3p
  53. Pundamilia nyererei pny-miR-103
  54. Python bivittatus (Burmese python) pbv-miR-103-3p
  55. Rattus norvegicus rno-miR-103-3p
  56. Salmo salar (Atlantic salmon) ssa-miR-103-3p
  57. Sarcophilus harrisii Sha-Mir-103-P2_3p (mature (guide))
  58. Scyliorhinus torazame Sto-Mir-103-P2_3p (mature (guide))
  59. Sphenodon punctatus Spt-Mir-103-P2_3p (mature (guide))
  60. Taeniopygia guttata (zebra finch) tgu-miR-103-3p
  61. Takifugu rubripes fru-miR-107
  62. Tetraodon nigroviridis (spotted green pufferfish) tni-miR-103
  63. Tor tambroides miR-103
  64. Tupaia chinensis (Chinese tree shrew) tch-miR-103a-3p
  65. Xenopus laevis (African clawed frog) xla-miR-103a-3p
  66. Xenopus tropicalis xtr-miR-103
Publications