ame-mir-9a: ame-mir-9a is a microRNA (miRNA) that is associated with queen-worker caste determination in Apis mellifera (A. mellifera) [PMC5374498]. However, in Bombus terrestris (B. terrestris), a different species of bumblebee, the expression of ame-mir-9a was not differentially expressed between queen- and worker-destined larvae [PMC5374498]. ame-mir-9a has been found to be involved in male development in bumblebees [PMC7785045]. It is expressed during honeybee early development and shows higher expression levels in adult worker thorax and abdomen compared to similar queen tissues, but higher levels of mir-9a occur in queen pupae [PMC3562263] [PMC2394756]. ame-mir-9a.F, a variant of ame-mir-9a, is expressed most strongly in worker thorax and abdomen compared to queen tissues [PMC2394756]. The expression of ame-mir-9a and ame-let-7, another miRNA, was found to be higher in males than females, suggesting their potential roles in male development [PMC6835379]. The expression of candidate loci ame-mir-9a was more strongly expressed in worker abdomens compared to queen abdomens [PMC2394756]. These findings suggest that ame-mir-9a may play a role in influencing caste differences and male development among honeybees and bumblebees.
Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset
View annotations in different species by clicking on species names.
Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.