v24

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Danio rerio (zebrafish) dre-let-7a URS0000416056_7955

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dre-let-7a: Dre-let-7a is a member of the let-7 miRNA family, originally isolated in zebrafish, and it has been found to interact with the 3'UTR genomic sequence of barramundi [PMC2292173]. In a study, dre-let-7a was identified as one of the top 5 most abundant miRNA families expressed at each stage [PMC3932949]. The abundance of dre-let-7a was validated using two-step real-time RT-PCR with the CFX96 Real-Time System [PMC6563994]. The comparative Ct method was employed to analyze the data and two miRNA housekeeping genes, dre-let-7a and dre-miR-10c, were used [PMC4647824]. RNA hybrid software analysis indicated that dre-let-7a has a binding strength of approximately -28.9 kcal/mol with a specific circRNA [PMC7759564]. In another study, it was found that dre-let-a is one of three miRNAs that bind to the 3'UTR region of GSTP1 in liver tissue [PMC7759564]. This research builds upon previous findings on GSTP1 and identifies three specific miRNAs (dre-let-a, ipu-miR143, and hsa-miR143) that interact with GSTP1 in C. plagiosum liver tissue [PMC7759564].

Genome locations

Gene Ontology annotations

Sequence

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UGAGGUAGUAGGUUGUAUAGUU

Taxonomic tree

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This sequence is found in 101 other species

  1. Alligator mississippiensis ami-let-7a-5p
  2. Anolis carolinensis (green anole) aca-let-7a-5p
  3. Ascaris suum (pig roundworm) asu-let-7-5p
  4. Ateles geoffroyi (black-handed spider monkey) microRNA let-7a-1
  5. Blattella germanica Bge-Let-7_5p (mature (guide))
  6. Bos taurus (cattle) bta-let-7a-5p
  7. Branchiostoma belcheri bbe-let-7a-5p
  8. Branchiostoma floridae (Florida lancelet) bfl-let-7a-5p
  9. Branchiostoma lanceolatum (amphioxus) Bla-Let-7-P3_5p (mature (guide))
  10. Brugia malayi (agent of lymphatic filariasis) bma-let-7
  11. Caenorhabditis brenneri cbn-let-7
  12. Caenorhabditis briggsae cbr-let-7
  13. Caenorhabditis elegans cel-let-7-5p
  14. Caenorhabditis remanei crm-let-7
  15. Callithrix jacchus (white-tufted-ear marmoset) cja-let-7a
  16. Callorhinchus milii (elephant shark) Cmi-Let-7-P2b4_5p (mature (guide))
  17. Canis lupus familiaris (dog) cfa-let-7a
  18. Capra hircus chi-let-7a-5p
  19. Cavia porcellus (domestic guinea pig) cpo-let-7a-5p
  20. Centruroides sculpturatus Csc-Let-7-P18b_5p (mature (guide))
  21. Cervus elaphus (red deer) cel-let-7a
  22. Chiloscyllium plagiosum microRNA cpl-let-7e
  23. Chrysemys picta bellii (western painted turtle) Cpi-Let-7-P2b4_5p (mature (guide))
  24. Chrysemys picta cpi-let-7a-5p
  25. Columba livia cli-let-7a-5p
  26. Crassostrea gigas Cgi-Let-7_5p (mature (guide))
  27. Cricetulus griseus (Chinese hamster) cgr-let-7a
  28. Cyprinus carpio (common carp) ccr-let-7a
  29. Dasypus novemcinctus dno-let-7a-5p
  30. Daubentonia madagascariensis (aye-aye) dma-let-7a
  31. Echinops telfairi Ete-Let-7-P2a1_5p (mature (guide))
  32. Eptatretus burgeri Ebu-Let-7-P2o6_5p (mature (guide))
  33. Equus caballus (horse) eca-let-7a
  34. Euprymna scolopes Esc-Let-7_5p (mature (guide))
  35. Gadus morhua gmo-let-7a-5p
  36. Gallus gallus gga-let-7j-5p
  37. Gekko japonicus Gja-Let-7-P2b4_5p (mature (guide))
  38. Gorilla gorilla (western gorilla) microRNA let-7a-1
  39. Haplochromis burtoni abu-let-7a
  40. Heligmosomoides polygyrus hpo-let-7-5p
  41. Homo sapiens (human) hsa-let-7a-5p
  42. Ictalurus punctatus ipu-let-7a
  43. Ixodes ricinus (castor bean tick) iri-let-7-5p
  44. Ixodes scapularis (black-legged tick) Isc-Let-7_5p (mature (guide))
  45. Lagothrix lagotricha (brown woolly monkey) microRNA let-7a-1
  46. Latimeria chalumnae (coelacanth) Lch-Let-7-P2b4_5p (mature (guide))
  47. Lemur catta microRNA let-7a-1
  48. Lepisosteus oculatus Loc-Let-7-P2b4_5p (mature (guide))
  49. Limulus polyphemus (Atlantic horseshoe crab) Lpo-Let-7-P17_5p (mature (guide))
  50. Lingula anatina Lan-Let-7_5p (mature (guide))
  51. Lottia gigantea (owl limpet) lgi-let-7
  52. Macaca mulatta (Rhesus monkey) mml-let-7a-5p
  53. Macaca nemestrina microRNA let-7a-1
  54. Maylandia zebra mze-let-7a
  55. Microcaecilia unicolor Mun-Let-7-P2b4_5p (mature (guide))
  56. Microcebus murinus (gray mouse lemur) mmr-let-7a
  57. Monodelphis domestica mdo-let-7a-5p
  58. Monopterus albus Mal-Let-7-P2b4b_5p (mature (guide))
  59. Mus musculus mmu-let-7a-5p
  60. Nautilus pompilius Npo-Let-7_5p (mature (guide))
  61. Neolamprologus brichardi (lyretail cichlid) nbr-let-7a
  62. Nomascus leucogenys (northern white-cheeked gibbon) nle-let-7a
  63. Octopus bimaculoides Obi-Let-7_5p (mature (guide))
  64. Octopus vulgaris Ovu-Let-7_5p (mature (guide))
  65. Ophiophagus hannah oha-let-7a
  66. Oreochromis niloticus (Nile tilapia) oni-let-7a
  67. Ornithorhynchus anatinus (platypus) Oan-Let-7-P2b4_5p (mature (guide))
  68. Oryctolagus cuniculus ocu-let-7a-5p
  69. Oryzias latipes ola-let-7a
  70. Otolemur garnettii oga-let-7a
  71. Ovis aries oar-let-7a
  72. Pan paniscus ppa-let-7a
  73. Pan troglodytes ptr-let-7a
  74. Papio hamadryas pha-let-7a
  75. Parasteatoda tepidariorum pte-let-7-5p
  76. Penaeus japonicus miR-let7
  77. Petromyzon marinus (sea lamprey) pma-let-7a
  78. Pongo pygmaeus (Bornean orangutan) ppy-let-7a
  79. Pristionchus pacificus ppc-let-7
  80. Pteropus alecto pal-let-7a-5p
  81. Ptychodera flava Pfl-Let-7_5p (mature (guide))
  82. Pundamilia nyererei pny-let-7a
  83. Python bivittatus (Burmese python) pbv-let-7a-5p
  84. Rattus norvegicus (Norway rat) rno-let-7a-5p
  85. synthetic construct RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3'... from None (PDB 4KRF, chain R)
  86. Saccoglossus kowalevskii sko-let-7
  87. Saguinus labiatus microRNA let-7a-1
  88. Saimiri boliviensis boliviensis sbo-let-7a
  89. Salmo salar (Atlantic salmon) ssa-let-7a-5p
  90. Sarcophilus harrisii Sha-Let-7-P2a1_5p (mature (guide))
  91. Scyliorhinus torazame Sto-Let-7-P2b3_5p (mature (guide))
  92. Sphenodon punctatus (tuatara) Spt-Let-7-P2b4_5p (mature (guide))
  93. Sus scrofa ssc-let-7a
  94. Taeniopygia guttata (zebra finch) tgu-let-7a-5p
  95. Takifugu rubripes fru-let-7a
  96. Tetraodon nigroviridis (spotted green pufferfish) tni-let-7a
  97. Tor tambroides (Thai mahseer) let-7a
  98. Tursiops truncatus (common bottlenose dolphin) let-7a
  99. Xenopus laevis (African clawed frog) xla-let-7a-5p
  100. Xenopus tropicalis (tropical clawed frog) xtr-let-7a
  101. Xenoturbella bocki Xbo-Let-7_5p (mature (guide))
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