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hsa-mir-2392: Hsa-mir-2392 is a microRNA that regulates multiple mRNAs, including CCND2, FAM241A, REL, POU2F1, and MICA [PMC7854084]. It has been proposed as a biomarker and therapeutic target for SARS-CoV-2 infection [PMC8686203]. The upregulation of hsa-mir-2392 has been observed in COVID-19 patients and is associated with poor outcomes [PMC9346380]. Hsa-mir-2392 is involved in downstream signaling pathways related to inflammation, glycolysis, and hypoxia [PMC9346380]. Hsa-mir-2392 is also targeted by hsa_circ_0006275 in MERS-CoV infection and regulates the expression of downstream targets such as MAP3K9, MYO15B, SPOCK1, MEF2C, USP15, and ZBTB11 [PMC9681929]. It has been studied in various animal models for SARS-CoV-2 infection to observe its conservation across species [PMC8481092].
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