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mmu-mir-101b: Mmu-mir-101b is a microRNA (miRNA) that is embedded in the intron of Rcl1 [PMC1449887]. The TransmiR database was used to predict potential transcription factors (TFs) of mmu-mir-101b, and 104 proteins were identified as potential TFs [PMC9903543]. To confirm that CEBPα is the TF of mmu-mir-101b, a 20,000-bp sequence in front of pre–miR-101b was input into the JASPAR database [PMC9903543]. The region that includes mmu-mir-101b may fold back upon the mRNA precursor, forming a stem loop to silence the Slc1a1 gene as a target [PMC1449887]. TargetScan analysis suggests that Slc1a1 is indeed a target of mmu-mir-101b [PMC1449887]. PCR primer sets for mmu-mir-101b were specific for mouse microRNAs [PMC5295159]. In a study, mmu-mir-101b was found to be downregulated [PMC9198802].
References:
[PMC9903543] TransmiR v2.0 database. http://www.cuilab.cn/transmir
[Additional file 1: Fig] PMC9903543
[http://jaspar.genereg.net/] PMC9903543
[PMC1449887] http://genes.mit.edu/targetscan
[http://genes.mit.edu/targetscan] PMC1449887
[http://genes.mit.edu/targetscan] PMC5295159
[PMC9198802]
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