oar-mir-27a: Oar-mir-27a is a sheep miRNA that is immune-related and accounts for about 98% of the top 20 sheep miRNAs [PMC7070426]. It has been found to have a targeting relationship with circLTBP1 in follicular and luteal phase ovarian tissues from monotocous and polytocous sheep [PMC8532869]. Oar-mir-27a, along with other miRNAs such as oar-miR-181a, oar-miR-136/oar-miR-127, and oar-miR-22-3p, has been found to be correlated with novel_circ_0017815 (RBPMS), novel_circ_0000417 (LOC106990833), novel_circ_0004065 (PAWR), and novel_circ_0016586 (INPP5F) in relation to sheep reproduction [PMC8532869]. Oar-mir-27a has also been identified as a target miRNA site in circRNAs through competitive endogenous RNA network analysis, along with other miRNAs such as oar-miR-16b, oar-miR-200a/b/c, oar-miR-181a, oar-miR-10a/b, and oar-miR432 [PMC8300399]. Furthermore, it has been found that these miRNAs, including oar-mir-27a, are correlated with novel_circ_0005497 (LTBP1), novel_circ_0006554 (INSR), novel_circ_0016082 (GREB1L), novel_circ_0005617 (IL1RL1), novel_circ_0005884 (SNX13), novel_circ_0014289 (CYP11A1), novel_circ_0008937 (COL12A1), novel_circ_0005617 (IL1RL1), novel_circ_0002309 (ITGAV), and novel_circ_0010140 (COL14A1) in relation to sheep fecundity [PMC8300399]. Based on miRNA target site prediction analysis, oar-mir-27a has been identified as a potential target of novel_circ_0005497 [PMC8300399].