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dre-let-7f: Dre-let-7f is a microRNA that is more highly expressed in ovaries compared to testes in zebrafish [PMC9495813]. In a study comparing different developmental stages of zebrafish larvae, the expression of dre-let-7f was found to be upregulated in day 13 larvae compared to day 7 larvae [PMC9610670]. Additionally, the expression levels of dre-let-7f increased steadily throughout the larval stages, indicating constant differentiation of larval cells [PMC9610670]. In comparison to the T_D larval stages, dre-let-7f expression was upregulated in the O_D and S_D larval stages [PMC9610670]. Dre-let-7f reached its highest expression level on the 13th day after hatching [PMC9610670]. Furthermore, when comparing different larval stages, dre-miR-129-1-3p and dre-miR1293p were also upregulated while novel_154 was downregulated along with drelet7f [PMC9610670]. These findings suggest that drelet7f plays a role in zebrafish ovarian development and differentiation during early developmental stages.
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