SCARNA22: SCARNA22 is a small Cajal body-specific RNA that has been found to be significantly evoked in challenged hBMECs [PMC8606740]. It is one of the four switch genes shared between Alzheimer's disease (AD) and vascular dementia (VaD) [PMC7313474]. SCARNA22 is selectively expressed in TC4 samples [PMC3511933]. It has been reported to be upregulated in multiple myeloma (MM) harboring the t(4;14) translocation and is localized within intron 18 of the WHSC1/MMSET gene [PMC3511933]. SCARNA22, also known as ACA11, is a novel H/ACA box snoRNA encoded within the introns of the WHSC1 gene, and its upregulation may suppress oxidative stress, facilitate cell proliferation, and protect cells from chemotherapy effects in t(4;14) MM cells [PMC8629011] [PMC9219770]. SCARNA22 is a noncoding RNA involved in the maturation of other RNA molecules and has been linked to human cancers. It is typically located in the introns of host genes and has been found to be upregulated in multiple myeloma harboring chromosomal translocations [PMC6416685]. This study provides the first evidence linking SCARNA22 with prostate cancer and disease progression [PMC6416685].