hsa-mir-2861: Hsa-mir-2861 is a microRNA (miRNA) that has been studied in various contexts. In a case study comparing miRNA profiles in subcutaneous adipose tissue (SAT) between obese and lean patients, hsa-mir-2861 was identified as one of the downregulated differentially expressed miRNAs [PMC7199309]. Similarly, in a study investigating exosomal miRNA profiles in SAT from obese and lean patients, hsa-mir-2861 was found to be downregulated [PMC6102639]. Hsa-mir-2861 has also been implicated in various other conditions. In different tissues and diseases, hsa-mir-2861 has been reported to be dysregulated along with other miRNAs [PMC4865051] [PMC6522747]. In the context of osteogenic differentiation, hsa-mir-2861 is one of the few miRNAs that have been associated with gene expression related to skeletal formation [PMC7116989]. Hsa-mir-2861 has also been identified as targeting E2F2 gene expression [PMC5221119]. Additionally, hsa-mir-2861 was found to be one of the statistically significant predictors of patient mortality within 3 years [PMC7999775]. Previous studies have reported negative modulation effects of hsa-mir-2861 on chordoma and basalioma through the mitogen-activated protein kinase pathway [PMC4581744]. Furthermore, upregulated expression levels of hsa-miR-345-3p, hsa-miR-371a-5p, and hsa-mir-2861 have been observed with the development of hepatic fibrosis; however, the detailed mechanism remains unclear [PMC4581744].