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Capra hircus (goat) microRNA chi-mir-206 precursor URS00003A7789_9925

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chi-mir-206: Chi-mir-206 is a microRNA that is associated with muscle development in goats [PMC8990838]. It is highly expressed in 7-month-old muscle tissue [PMC8990838]. In the longissimus dorsi muscle of goats, chi-mir-206 is one of the top 10 differentially expressed microRNAs [PMC8314457]. It is also highly expressed in the skeletal muscles of 7-month-old goats [PMC6687162]. The downregulation of chi-mir-206 in post-weaning goats suggests a depressed muscle development function [PMC6687162]. In addition to chi-mir-206, other microRNAs related to muscle development, such as chi-miR-133a/b, are also downregulated in post-weaning goats [PMC6687162]. These findings provide important information about weaning stress-induced growth retardation in livestock [PMC6687162]. Chi-mir-206 is part of a network that regulates multiple targets involved in muscle development, such as ASB14 and Schlafen 11 (SLFN11) [PMC6687162]. It also plays a role in regulating cell proliferation along with other microRNAs like chi-miR-99b-3p and chi-miR-224 [PMC6687162]. Furthermore, chi-mir-206 has been found to be highly expressed in group B but expressed at low levels in groups A and C when comparing different stages of small follicles in goats' ovaries. This suggests that the expression of this microRNA is time-specific and may have specific functions during certain stages of follicle development.

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Gene Ontology annotations

Sequence

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UGCUUCCCAAGGCCACAUGCUUCUUUAUAUCCCCAUACGGAUUACUUUGCUAUGGAAUGUAAGGAAGUGUGUGGUUUCGGCGAGCG

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