eca-mir-92a: Eca-mir-92a is an orthologous pre-miRNA that is part of a group of miRNAs, including eca-mir-19b, eca-mir-20a, eca-mir-19a, eca-mir-18a, and eca-mir-17 [PMC3005926]. In a study comparing plasma and synovial fluid (SF), seven miRNAs were found to be differentially expressed (DE), including eca-miR-451, eca-miR-25, eca-miR-215, eca-mir-92a, eca-miR-let7c, eca-miR-486-5p, and eca-miR23a [PMC9393553]. These miRNAs were also found to be DE in plasma and SF-derived extracellular vesicles (EVs) when comparing different time points [PMC9393553]. Ten of these miRNAs were identified in multiple pairwise comparisons [PMC9393553]. Additionally, four snoRNAs (U3, snord15 snord46 and snord58) were identified temporally between specific time points [PMC9393553]. Among the highly expressed miRNAs in the total counts analyzed in the study (86% of total counts), the top five included ecamiR4865p ,eca mir92a ,eca mir191a ,eca mir4235p ,and ica mir148 a[PMC5748701]. [PMC3005926] - Liang et al. "Identification of differentially expressed microRNA between synovial tissue-derived mesenchymal stem cells from osteoarthritis patients and donor matched healthy controls" - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005926/ [PMC9393553] - Li et al. "Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis" - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393553/ [PMC5748701] - Li et al. "Identification of synovial fluid microRNA signature in knee osteoarthritis: differentiating early- and late-stage knee osteoarthritis" - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748701/