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hsa-mir-4635: Hsa-mir-4635 is a microRNA (miRNA) that has been identified in studies related to cardiac diseases and obesity. It has been suggested that hsa-mir-4635, along with other miRNAs such as hsa-Mir-4710, hsa-Mir-3934, hsa-Mir-665, and has-Mir-4695-5p, may play a role in regulating cardiac marker genes during hypertrophy and other cardiac diseases [PMC3842578]. These miRNAs have been found to be associated with ANP, BNP, TNNT2, TNNI3, α-Actinin, and MYH-7 [PMC3842578]. In a study on non-small cell lung cancer (NSCLC) patients, hsa-mir-4635 was found to have a significant correlation with overall survival (OS) along with other miRNAs such as hsa-miR-146b and hsa-miR-27b [PMC8281680]. The expression values of these miRNAs were used to calculate a TIM-Sig score for predicting OS in NSCLC patients [PMC8281680]. Hsa-mir-4635 was also used as one of the primers in a study on obesity-related gene regulation [PMC6527545]. It was found that downregulated expression of hsa-mir-4635 was associated with upregulated genes in patients with obesity [PMC6102639]. These findings suggest that hsa-mir-4635 may have important regulatory functions in various disease contexts.
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