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Gallus gallus (chicken) gga-miR-206 URS000034B6F5_9031

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gga-mir-206: gga-mir-206 is a muscle-specific miRNA that has been identified in chickens [PMC7797159]. It has been found to affect preadipocyte proliferation and differentiation in chickens [PMC9258119]. The overexpression of gga-mir-206 inhibits adipogenesis by downregulating its target gene, Kruppel-like factor 4 (KLF4) [PMC9258119]. gga-mir-206 has also been found to be differentially expressed in embryonic skeletal muscle tissues between meat-type broilers and egg-type layer chickens [PMC4849015]. It is the most abundant miRNA in skeletal muscles of broilers and layers, consistent with its role in skeletal muscle development [PMC3107184]. gga-mir-206 has also been identified as a target of circRNA derived from the RBFOX2 gene [PMC5824844]. It is associated with genes such as ankyrin repeat domain 1 (ANKRD1), ankyrin repeat domain 12 (ANKRD12), MAFF, FOS, osteocalcin-like protein OC3 (OC3), phytate kinase 2 (IP6K2), and Cyclin C (CCNC) [PMC9689937]. The expression of gga-mir-206 is downregulated by miR-M2-5p, resulting in the upregulation of Pax3, Bcl-2, and Bcl-xL and inhibition of CEF cell apoptosis [PMC7669912]. The expression of gga-mir-206 has also been confirmed by real-time RT-PCR [PMC3496578]. In addition to its role in muscle development, gga-mir-206 has also been found to target the FoxO signaling pathway and the MAPK signaling pathway in chickens [PMC6815035].

Genome locations

Gene Ontology annotations


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This sequence is found in 52 other species

  1. Alligator mississippiensis (American alligator) ami-miR-206-3p
  2. Anolis carolinensis (green anole) Aca-Mir-1-P2_3p (mature (guide))
  3. Bos taurus (cattle) bta-miR-206
  4. Callithrix jacchus cja-miR-206
  5. Canis lupus familiaris (dog) cfa-miR-206
  6. Cavia porcellus (domestic guinea pig) cpo-miR-206-3p
  7. Chrysemys picta bellii (western painted turtle) Cpi-Mir-1-P2_3p (mature (guide))
  8. Chrysemys picta (Painted turtle) cpi-miR-206-3p
  9. Columba livia cli-miR-206-3p
  10. Cricetulus griseus cgr-miR-206
  11. Cyprinus carpio (common carp) ccr-miR-206
  12. Danio rerio dre-miR-206-3p
  13. Dasypus novemcinctus dno-miR-206-3p
  14. Echinops telfairi Ete-Mir-1-P2_3p (mature (guide))
  15. Equus caballus (horse) eca-miR-206
  16. Gadus morhua gmo-miR-206-3p
  17. Gekko japonicus Gja-Mir-1-P2f_3p (mature (guide))
  18. Gorilla gorilla gorilla ggo-miR-206 (MIR206)
  19. Gorilla gorilla (western gorilla) ggo-miR-206
  20. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-206
  21. Homo sapiens hsa-miR-206
  22. Ictalurus punctatus ipu-miR-206
  23. Latimeria chalumnae Lch-Mir-1-P2_3p (mature (guide))
  24. Lepisosteus oculatus Loc-Mir-1-P2_3p (mature (guide))
  25. Macaca mulatta mml-miR-206
  26. Macaca nemestrina mne-miR-206
  27. Maylandia zebra (zebra mbuna) mze-miR-206
  28. Microcaecilia unicolor Mun-Mir-1-P2_3p (mature (guide))
  29. Monodelphis domestica Mdo-Mir-1-P2_3p (mature (guide))
  30. Monopterus albus Mal-Mir-1-P2a_3p (mature (guide))
  31. Mus musculus mmu-miR-206-3p
  32. Neolamprologus brichardi nbr-miR-206
  33. Ophiophagus hannah (king cobra) oha-miR-206
  34. Oreochromis niloticus oni-miR-206
  35. Ornithorhynchus anatinus (platypus) oan-miR-206-3p
  36. Oryctolagus cuniculus ocu-miR-206-3p
  37. Ovis aries Pri-miR206
  38. Pan troglodytes ptr-miR-206
  39. Paralichthys olivaceus pol-miR-206-3p
  40. Pongo pygmaeus (Bornean orangutan) ppy-miR-206
  41. Pteropus alecto (black flying fox) pal-miR-206-3p
  42. Pundamilia nyererei pny-miR-206
  43. Python bivittatus (Burmese python) pbv-miR-206-3p
  44. Rattus norvegicus rno-miR-206-3p
  45. Salmo salar ssa-miR-206-3p
  46. Sarcophilus harrisii Sha-Mir-1-P2_3p (mature (guide))
  47. Sphenodon punctatus Spt-Mir-1-P2_3p (mature (guide))
  48. Taeniopygia guttata Tgu-Mir-1-P2_3p (mature (guide))
  49. Tetraodon nigroviridis Tni-Mir-1-P2a_3p (mature (guide))
  50. Tor tambroides (Thai mahseer) miR-206-3p
  51. Xenopus laevis (African clawed frog) xla-miR-206-3p
  52. Xenopus tropicalis xtr-miR-206