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Homo sapiens (human) small nucleolar RNA, H/ACA box 11 (SNORA11) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, H/ACA box 11 (SNORA11) URS000032FEC4_9606

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SNORA11: SNORA11 is a small nucleolar RNA (snoRNA) that has been implicated in various diseases, including hepatocellular carcinoma (HCC) and ameloblastoma. In HCC, SNORA11 is upregulated in the high-risk group and is considered a risk factor for the disease [PMC9524901]. It is also associated with the infiltration of T follicular helper cells (TFH) and Th2 cells [PMC9524901]. In ameloblastoma, SNORA11 is overexpressed and has been proposed as a potential biomarker for the disease [PMC7920560]. Additionally, SNORA11 has been found to be involved in the conversion of pseudouridine to uridine [PMC6633893]. In breast cancer, SNORA11 is upregulated in luminal breast cancer and associated with better outcomes, lower grade tumors, and receptor-positive status [PMC9803687]. It also shows a positive correlation with tumor size in ameloblastoma [PMC5354851]. Furthermore, SNORA11 has been identified as a guide RNA for positioning modifications on U2 snRNA [PMC6984369]. Overall, SNORA11 plays diverse roles in different diseases and may have diagnostic and prognostic value.

Genome locations

Gene Ontology annotations

Sequence

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GGGGUGUGCUCAGAGCAGGGGGCCCAAAGAAUGGCUCCUCUGUUUACAACACACCCAACAGGAAUCUGGGGUCAUUGUGAUGAGGGCGUCAAACUUGUGGCUUCCCUAUGAACAAACGUCCCCCAACACCU

Taxonomic tree

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2D structure Publications