v24

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Homo sapiens (human) NCBP2 antisense RNA 1 (NCBP2-AS1) URS000032F1F5_9606

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NCBP2-AS1: NCBP2-AS1 is a long non-coding RNA (lncRNA) that has been found to be negatively correlated with the expression of PD-1, a protein involved in immune regulation [PMC9590147]. In a ceRNA regulatory network, NCBP2-AS1 was found to interact with hsa-miR-34c and hsa-miR-363 [PMC7541229]. NCBP2-AS1 was also identified as one of the 14 risky RNAs in a prognostic signature for esophageal carcinoma [PMC7541229]. Additionally, the expression level of NCBP2-AS1 was found to be related to PD-1 expression in the context of immune checkpoints [PMC8883231]. The dysregulation of NCBP2-AS1 has been implicated in the progression of esophageal carcinoma [PMC8486540]. In summary, NCBP2-AS1 is an lncRNA that is negatively correlated with PD-1 expression and is involved in ceRNA regulatory networks and prognostic signatures for esophageal carcinoma. Its dysregulation may play a role in disease progression.

Genome locations

Gene Ontology annotations

Sequence

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GCCACAACCUUGAUGCUUUACGUGCUCAUAGAUCUUUCUCUGAGUUUAGGGGAAAAUGUAGUGAUCACUAAAAACAAAACAGAGCUCACUUUCUUAAUGGGCUUCCAAAUUGGGAUGACAGGAUGAAGCCAGAGACUUAAGCAUAUAACUGGGCUUCAUCCAACACACCUGACAGACAAAGCCCUGGGUCCAAAAUGGCUCAUCGGGGUCAGGCGCGGUGGCUCAUGCCUGUAAUCCCAGCACUUUGGGAGGCUGAGGUGGGUAGGAUCACUUAGGCUCAGGAGGUUGAGGCUGCGUGAGCCGUGAUUGCGCCACUGCACUUCAGCCUAGGCAAUAAAGCGAGACUCUGUCUCAAAAAAUAAAAUACAUUAACUGAAUAAAUUUUUUUUUUUUGAGAAGGAAUAUCGCUCUGUUGCCCAGGGCCUUCCCGUCUCGCGGCCCGGCCUCCCUCACCCGGAAGUGCUGGUCCCGGUACUGGCUCAGCUCCACGUAGGAGUCGCUGCGCAGCGCCUUCAGGAGGCCACCCGACAUAGUGCAGAGAAGCGGACCACAAUGCGGCGAC

Taxonomic tree

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Publications