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Homo sapiens (human) hsa-miR-378b URS0000328C0D_9606

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hsa-mir-378b: Hsa-mir-378b is a microRNA that has been identified in the context of Type 1 Diabetes (T1D) and is involved in the regulation of various target genes and transcription factors (TFs) [PMC8028841]. In T1D, hsa-mir-378b has been found to target POLR2A, a gene involved in RNA transcription [PMC8028841]. Additionally, hsa-mir-378b has been shown to target IGF1R, a gene associated with growth and development [PMC6595612]. Hsa-mir-378b is part of a panel of 16 miRNA markers that have been identified in various diseases [PMC6595612]. In the context of tumor development and progression, hsa-mir-378b has been found to interact with upstream long non-coding RNAs (lncRNAs) based on the ceRNA hypothesis [PMC9597465]. Furthermore, hsa-mir-378b has been analyzed in miRNA sequencing data sets along with other miRNAs such as hsa-miR-182-5p and hsa-miR-192-5p [PMC4822037]. Downregulation of hsa-mir-378b suggests increased expression of target genes such as CHP1, HSPA9, MAPK1, PIK3CD/G, PPP3R1/2, PRKCQ, and VEGFA [PMC9781133]. Overall, these findings highlight the involvement of hsa-mir-378b in various biological processes and disease contexts.

Genome locations

Gene Ontology annotations

Sequence

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ACUGGACUUGGAGGCAGAA

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Publications