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hsa-mir-454: Hsa-mir-454 is a microRNA that has been found to be associated with day-3 embryo quality [PMC6242846]. It is one of seven EV-miRNAs that have been identified in this context [PMC6242846]. Additionally, hsa-mir-454 has been found to be down-regulated at TP 2-8 compared to TP 1 in patients without metastases [PMC4599298]. Furthermore, hsa-mir-454 has been identified as one of the miRNAs that may regulate TNF-α expression [PMC7675078]. In a study examining differentially expressed miRNAs, hsa-mir-454 was found to be upregulated in the ceRNA network of BRCA patients aged ≤ 39 years [PMC8097183]. Overall, hsa-mir-454 has been implicated in various biological processes and may have a role in embryo quality, metastasis, TNF-α expression regulation, and BRCA ceRNA networks.
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