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hsa-mir-4324: Hsa-mir-4324 is a microRNA that has been studied in relation to bladder cancer and triple-negative breast cancer (TNBC) [PMC7380276] [PMC6031086] [PMC6357448] [PMC9952540]. In bladder cancer, hsa-mir-4324, along with eight other microRNAs, provides prognostic and predictive value for patients with urothelial carcinoma of the bladder [PMC7380276]. Another study found that hsa-mir-4324 is one of the microRNAs that are downregulated in bladder cancer [PMC6031086]. In TNBC, reduced expression of hsa-mir-4324 was found to correlate with low PTEN expression, indicating a more aggressive form of the disease [PMC6357448]. Additionally, hsa-mir-4324 was identified as one of the miRNAs that positively correlated with PTEN-deficiency in TNBC [PMC6357448]. The expression levels of hsa-mir-4324 were also found to correlate positively with PTEN-loss in bladder cancer [PMC6357448]. Furthermore, a study discovered that hsa-mir-4324 is one of the downregulated miRNAs that regulate disease-associated genes in a network analysis [PMC9952540]. Overall, these findings suggest that hsa-mir-4324 may play a role in the development and progression of bladder cancer and TNBC.
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