hsa-mir-4328: Hsa-mir-4328 is a microRNA that has been found to be down-regulated in mucinous cystadenocarcinoma compared to mucinous cystadenoma [PMC5228663]. It is also suggested that down-regulation of hsa-mir-4328 may be a novel biomarker for pancreatic cancer progression [PMC5228663]. Hsa-mir-875-3p is closely linked to hsa-mir-4328 in a co-regulation network and both of them are down-regulated [PMC5228663]. However, there are only a few studies that have reported on the alteration of hsa-mir-4328 in cancers [PMC5228663]. In the co-regulation network, there are strong relationships between hsa-miR-875-3p, hsa-mir-4328, hsa-miR-24, and hsa-miR-31; hsa-miR-338-5p and hsa-miR543; and between other microRNAs as well [PMC5228663]. These findings suggest the importance of these microRNAs in the regulation of gene expression. Overall, the down-regulation of both hsa-mir-4328 and hsa-mir875 3p may have implications for cancer progression and could potentially serve as biomarkers for pancreatic cancer. However, further research is needed to fully understand their roles in cancer development and progression.