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bta-mir-204: Bta-mir-204 is a miRNA that was identified as one of the highly enriched miRNAs in a previous study [PMC7505075]. It is classified as a non-DA miRNA [PMC7505075]. In the study, bta-mir-204 was found to negatively regulate the expression of BoLA (Bovine Leukocyte Antigen) by directly binding to its complementary sequence in the 3'-UTR (3'-untranslated region) of BoLA in a sequence-specific manner [PMC8056107]. This suggests that bta-mir-204 plays a role in regulating the expression of BoLA, which is involved in immune responses and disease resistance in cattle [PMC8056107]. The presence of bta-mir-204 among the top 20 abundant miRNAs indicates its potential importance and involvement in various biological processes [PMC7505075]. The identification and characterization of bta-mir-204 provide insights into the regulatory mechanisms underlying immune responses and disease resistance in cattle. Further studies may be warranted to explore its specific functions and potential applications.
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