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SNORD55: SNORD55 is a small nucleolar RNA (snoRNA) that has been implicated in various diseases, including hepatocellular carcinoma and non-small cell lung cancer (NSCLC) [PMC9818347]. In hepatocellular carcinoma, four snoRNAs, including SNORD55, were found to be upregulated in the plasma of cancer patients compared to healthy donors [PMC9818347]. However, there is no mention of the downregulation of SNORD116-3 and SNORD116-24 in hepatocellular carcinoma patients [PMC9818347]. In the context of NSCLC, a study enrolled 189 healthy donors and 290 NSCLC patients to investigate the differential expression of SNORD55 in tumor-educated platelets (TEPs) [PMC7919130]. TEPs were collected from these individuals and subjected to quantitative polymerase chain reaction (qPCR) analysis [PMC7919130]. The study aimed to determine if SNORD55 expression levels could serve as a potential biomarker for NSCLC diagnosis or prognosis [PMC7919130]. These findings highlight the potential role of SNORD55 as a biomarker for various diseases and emphasize the importance of further research in understanding its functional significance [PMC9818347][PMC7919130].
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